CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1421
Family Name Leukotriene B4 receptor 1 Ligand SC-51146 Family
No. of Seeds 6 No. of Other Members 315
Family Centroid CFAMM00238400 Functional Category Investigative Drug with Natural Product
Superfamily Leukotriene B4 receptor 1 Ligand SC-51146 Superfamily
Class Class 544

Cousin Family NamesSeedsMembers
Alpha-1 adrenergic receptor ligand arylethanolamine derivative... 4 37
Beta adrenergic receptor Ligand Levobunolol Family 6 133
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
DNA Binder Methoxsalen Family 10 1638
Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Hidrosmin family 14 61
Ipriflavone family 62 2480
Rotenone family 16 107
Agrimophol family 10 22
Cyclin-dependent kinase 2 Inhibitor Flavopiridol Family 4 124
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
Integrin alpha-4 Inhibitor Firategrast Family 3 93
Microsomal triglyceride transfer protein large subunit Inhibit... 3 103
Heat shock protein 90, putative Inhibitor KW-2478 Family 1 14
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Tyrosine-protein phosphatase non-receptor type 1 Ligand PNU177... 1 5
cAMP-dependent protein kinase type II-beta regulatory subunit ... 34 81
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Peroxisome proliferator-activated receptor gamma and Peroxisom... 2 4
DNA-dependent protein kinase catalytic subunit Inhibitor 7-pro... 5 49
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Beta-2 adrenergic receptor Ligand Gnf-pf-1694 Family 4 70
Protein kinase C gamma type and Protein kinase C alpha type In... 2 1
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Androgen receptor Ligand Palodesangren E Family 12 43
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Peroxisome proliferator-activated receptor delta and Peroxisom... 20 8
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 8 12
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 7
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 2 18
Mu-type opioid receptor ligand 3-[(3R,4R)-1-[(2,4-dimethoxyphe... 2 4
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-ben... 5 334
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2,6-... 16 23
Prostaglandin E2 receptor EP4 subtype ligand 4-[(1S)-1-[[2-(tr... 2 1
Prostaglandin D2 receptor 2 and Chemoattractant receptor-homol... 1 1
Peroxisome proliferator-activated receptor gamma ligand (9aS)-... 4 44
Melanin-concentrating hormone receptor 1 and Potassium voltage... 12 53
Potassium voltage-gated channel subfamily H member 2 and Melan... 5 4
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 3 191
Estrogen receptor ligand 2-(3-hydroxy-6-oxoxanthen-9-yl)-5-[[4... 1 2
Peroxisome proliferator-activated receptor delta and Peroxisom... 13 0
C-C chemokine receptor type 1 and Chemokine (C-C motif) recept... 11 15
C-C chemokine receptor type 1 and Chemokine (C-C motif) recept... 1 16
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 11
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 2
Acetylcholinesterase and Butyrylcholinesterase inhibitor [3-[[... 1 65
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 16 2
Free fatty acid receptor 1 ligand (3R,4R)-3-[4-(3,4-dimethylph... 4 4
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 4 3
Inosine-5'-monophosphate dehydrogenase 2 inhibitor (E)-6-(4-hy... 1 10
Breast cancer type 1 susceptibility protein and Huntingtin inh... 1 7
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 2 110
Cathepsin D inhibitor (E)-N-butyl-4-[1-(3,4,5-trimethoxybenzoy... 1 3
Inosine-5'-monophosphate dehydrogenase 2 and Inosine-5'-monoph... 1 14
Malate dehydrogenase, mitochondrial and Lactate dehydrogenase ... 1 1
Acetylcholinesterase and Butyrylcholinesterase inhibitor (2Z)-... 2 10
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07R9XR fa... 1 7
Putative NP ZINC31164438 Family 18 0
Putative NP ZINC02127056 Family 4 1
Putative NP ZINC08790868 Family 10 0
NP 2-((5-hydroxy-2,2-dimethyl-4-oxochroman-7-yl)oxy)-n-(3-meth... 18 0
NP 2-((1'-acetyl-4-oxospiro[chroman-2,4'-piperidin]-7-yl)oxy)-... 5 0
NP 1,3,8-trihydroxy-6-methyl-2-(morpholinomethyl)anthracene-9,... 2 0
4-methyl-7-[(4-methylpiperazin-1-ium-1-yl)methyl]-3-oxo-1-benz... 14 0
1-benzofuran-3-one NP ZINC02445091 Family 23 0
Putative NP ZINC20357755 Family 11 0
6-hydroxy-7-(morpholin-4-ylmethyl)-1-benzofuran-3-one NP ZINC2... 7 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00238283 CHEMBL328492 Bioactive SC-51146
CFAMM00238301 DNC004433 Investigative Drug SC-50676
CFAMM00238300 DNC004430 Investigative Drug SC-52073
CFAMM00238526 DNC004412 Investigative Drug SC-50135
CFAMM00238400 DNC004421 Investigative Drug SC-51146
CFAMM00238399 DNC004423 Investigative Drug SC-53229

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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