CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1440
Family Name Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 6-amino-benzothiazole-2-sulfonic Acid Amide Family
No. of Seeds 5 No. of Other Members 24
Family Centroid CFAMM00238986 Functional Category Investigative Drug with Natural Product
Superfamily Aldose reductase and AP endonuclease APE1 Binder Superfamily
Class Class 1698

Cousin Family NamesSeedsMembers
AP endonuclease APE1 Inhibitor 1,3-bis(1,3-benzothiazol-2-ylth... 1 12
Prothrombin Inhibitor Benzothiazole Family 1 29
Nitric oxide synthase, brain and Nitric oxide synthase, endoth... 2 11
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-(2,6... 5 9
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-(met... 4 6
Mitogen-activated protein kinase 1 and Retinal dehydrogenase 1... 1 5
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2,2,3,... 3 1
Amyloid beta A4 protein and Luciferin 4-monooxygenase inhibito... 11 46
Microtubule-associated protein tau inhibitor Toluidine Blue O ... 2 0
Sphingosine 1-phosphate receptor 4 and 3-hydroxyacyl-CoA dehyd... 1 1
(E)-2-(1,3-benzothiazol-2-yl)-3-thiophen-2-ylprop-2-enenitrile... 1 0


External ID

Functional Category

Molecule Name

CFAMM00238978 CHEMBL141753 Bioactive 6-(1,1,2,2,3,3,4,4,4-nonafluorobutylsulfonylamino)-1,3-benzothiazole-2-sulfonamide
CFAMM00238982 CHEMBL141351 Bioactive 6-(trifluoromethylsulfonylamino)-1,3-benzothiazole-2-sulfonamide
CFAMM00238998 DNC004896 Investigative Drug Benzothiazole-2-sulfonic acid amide
CFAMM00238989 DNC005121 Investigative Drug 6-Nitro-benzothiazole-2-sulfonic acid amide
CFAMM00238986 DNC004469 Investigative Drug 6-Amino-benzothiazole-2-sulfonic acid amide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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