CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1443
Family Name Aromatase Inhibitor 3-((1h-imidazol-1-yl)methyl)-9h-xanthen-9-one Family
No. of Seeds 6 No. of Other Members 17
Family Centroid CFAMM00239022 Functional Category Investigative Drug
Superfamily Aromatase Binder Superfamily
Class Class 1096

Cousin Family NamesSeedsMembers
Thromboxane-A synthase Inhibitor Dazoxiben Family 2 32
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 2 4
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 1 14
Aromatase Inhibitor 5-bromo-8-imidazol-1-ylmethyl-chromen-4-on... 2 0
Aromatase Inhibitor 2-imidazol-1-yl-7-methoxy-3-phenyl-chromen... 1 4
Aromatase Inhibitor 4'-cyano-3-(imidazolylmethyl)flavone Family 4 3
Aromatase Inhibitor 4'-bromo-3-(imidazolylmethyl)flavone Family 2 0
Aromatase Inhibitor 3-(imidazolylmethyl)-4'-nitroflavone Family 4 1
Aromatase Inhibitor 4-((1h-imidazol-1-yl)methyl)-2h-chromen-2-... 3 69
Aromatase Inhibitor 4-(2-(1h-imidazol-1-yl)ethoxy)-2h-chromen-... 2 6
Protein farnesyltransferase subunit beta Inhibitor A-313326 Fa... 85 149
Potassium voltage-gated channel subfamily H member 2 Ligand (1... 64 70
Aromatase inhibitor SureCN6049788 family 1 2
Cytochrome P450 26A1 and Cytochrome P450 3A4 inhibitor 3-[6-[(... 14 26
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 5 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 3
Thromboxane-A synthase inhibitor AGN-PC-00M20O family 2 0
Thromboxane-A synthase inhibitor AGN-PC-00NE9O family 4 1
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 0
Aromatase and Thromboxane-A synthase inhibitor tetrahydrobenzo... 1 0


External ID

Functional Category

Molecule Name

CFAMM00239022 DNC004478 Investigative Drug 3-((1H-imidazol-1-yl)methyl)-9H-xanthen-9-one
CFAMM00239027 DNC010875 Investigative Drug 2-Imidazol-1-ylmethylxanthen-9-one
CFAMM00239026 DNC010872 Investigative Drug 1-Imidazol-1-ylmethylxanthen-9-one
CFAMM00239044 DNC004495 Investigative Drug 7-((1H-imidazol-1-yl)methyl)-4H-chromen-4-one
CFAMM00239025 DNC010870 Investigative Drug 4-Imidazol-1-ylmethylxanthen-9-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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