CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1461
Family Name Aromatase Inhibitor 1-(7-methoxy-2-phenyl-chroman-4-yl)-1h-imidazole Family
No. of Seeds 2 No. of Other Members 22
Family Centroid CFAMM00239493 Functional Category Investigative Drug
Superfamily Aromatase and Cytochrome P450 3A4 Binder Superfamily
Class Class 1096

Cousin Family NamesSeedsMembers
Aromatase Inhibitor 4'-cyano-3-(imidazolylmethyl)flavone Family 4 3
Aromatase Inhibitor 4-((1h-imidazol-1-yl)methyl)-2h-chromen-2-... 3 69
Aromatase Inhibitor 4-(2-(1h-imidazol-1-yl)ethoxy)-2h-chromen-... 2 6
Cytochrome P450 3A4 Inhibitor SK&F-96365 Family 2 26
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor Rac-4'-(1-i... 5 9
Aromatase inhibitor AGN-PC-075MOK family 1 4
Cytochrome P450 26A1 and Cytochrome P450 3A4 inhibitor 3-[6-[(... 14 26
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 5 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 3
Aromatase inhibitor AGN-PC-093P98 family 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00239507 DNC004527 Investigative Drug 4-Imidazol-1-yl-2-phenyl-chroman-7-ol
CFAMM00239493 DNC004513 Investigative Drug 1-(7-Methoxy-2-phenyl-chroman-4-yl)-1H-imidazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27518 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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