CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1499
Family Name Fatty-acid amide hydrolase 1 Inhibitor (z)-1-(benzo[d]oxazol-2-yl)octadec-9-en-1-one Family
No. of Seeds 2 No. of Other Members 27
Family Centroid CFAMM00240656 Functional Category Investigative Drug
Superfamily Leukotriene A-4 hydrolase and Fatty-acid amide hydrolase 1 Binder Superfamily
Class Class 2136

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Nitric oxide synthase, endothelial Inhibitor Acclaim Family 2 15
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Benoxapr... 1 76
Substance-P receptor Ligand R 673 Family 2 127
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxaz... 10 142
Oestrogen receptor and Estrogen receptor beta Ligand 2-naphtha... 4 51
Oestrogen receptor and Estrogen receptor beta Ligand 2-(6-hydr... 9 22
Arachidonate 5-lipoxygenase Inhibitor 5-chloro-n-phenylbenzo[d... 3 15
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Leukotriene A-4 hydrolase Inhibitor 2-[4-(2-azepan-1-ylethoxy)... 5 15
5-hydroxytryptamine receptor 3A and Neuronal acetylcholine rec... 2 26
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 1 4
Fatty-acid amide hydrolase 1 Inhibitor 3-(benzo[d]oxazol-2-yl)... 1 6
Arachidonate 5-lipoxygenase Inhibitor 5-methyl-n-phenylbenzo[d... 5 13
Arachidonate 5-lipoxygenase Inhibitor 5-methoxy-n-phenylbenzo[... 2 4
Muscarinic acetylcholine receptor M3 ligand [(3R)-1-[3-(1,3-be... 3 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 21
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 14 24
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 4jj ... 1 1
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 5a f... 2 1
Sigma non-opioid intracellular receptor 1 ligand 2-[4-(4-cyclo... 2 5
Reverse transcriptase/RNaseH inhibitor AC1LAJTX family 2 0
Neutrophil elastase inhibitor 1-[4-(1,3-benzoxazol-2-ylsulfany... 3 0
D(4) dopamine receptor ligand SureCN8704964 family 1 2
Reverse transcriptase/RNaseH inhibitor 3-[2-(4,7-difluoro-1,3-... 3 1
Glucocorticoid receptor and Progesterone receptor ligand (8S,1... 2 0
Cholesteryl ester transfer protein inhibitor AGN-PC-07R9U4 family 1 1
Arachidonate 5-lipoxygenase inhibitor (4E)-4-[(E,4Z)-4-(3H-1,3... 6 6
Reverse transcriptase/RNaseH inhibitor 3-(1,3-benzoxazol-2-ylm... 1 0
2-enenitrile NP ZINC05025155 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00240639 DNC011210 Investigative Drug S-benzo[d]oxazol-2-yl O-butyl carbonothioate
CFAMM00240656 DNC004656 Investigative Drug (Z)-1-(benzo[d]oxazol-2-yl)octadec-9-en-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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