CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1500
Family Name Fatty-acid amide hydrolase 1 Inhibitor 1-(oxazolo[4,5-b]pyridin-2-yl)dodecan-1-one Family
No. of Seeds 19 No. of Other Members 34
Family Centroid CFAMM00240667 Functional Category Investigative Drug
Superfamily Fatty-acid amide hydrolase 1 Inhibitor 1-(oxazolo[4,5-b]pyridin-2-yl)dodecan-1-one Superfamily
Class Class 2137

Cousin Family NamesSeedsMembers
Substance-P receptor Ligand R 673 Family 2 127
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 37
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxaz... 10 142
Vascular endothelial growth factor receptor 1 and Vascular end... 4 44
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-[5-(4-hydroxyphe... 4 36
5-hydroxytryptamine receptor 3A and Neuronal acetylcholine rec... 2 26
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Peroxisome proliferator-activated receptor delta ligand SureCN... 8 19
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 21
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 6 9
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 4 15
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Inosine-5'-monophosphate dehydrogenase inhibitor SureCN1318237... 2 12
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
Fatty-acid amide hydrolase 1 inhibitor [(2S)-6-phenoxy-1,2,3,4... 3 6
Fatty-acid amide hydrolase 1 and Liver carboxylesterase 1 inhi... 2 2
Histamine H3 receptor ligand 2-(4-piperidin-1-ylpiperidin-1-yl... 1 3
Sphingosine 1-phosphate receptor 1 ligand 6-[2-[4-phenyl-3-(tr... 2 3
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Peroxisome proliferator-activated receptor gamma and Peroxisom... 3 0
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 4jj ... 1 1
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 5a f... 2 1
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 5
Mitogen-activated protein kinase 14 inhibitor 4-[4-(4-fluoroph... 1 5
Adenosine kinase inhibitor AGN-PC-0757MS family 2 0
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-009CXX family 1 0
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 4 4
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 1 0
Sorbitol dehydrogenase inhibitor SureCN6298924 family 4 4
Cholesteryl ester transfer protein inhibitor AGN-PC-09QM3I family 1 9
Diacylglycerol O-acyltransferase 1 inhibitor SureCN2789698 family 2 8
Histamine H3 receptor ligand 9-[2-(4-piperidin-1-ylpiperidin-1... 1 3
Fatty-acid amide hydrolase 1 inhibitor 7-phenyl-1-[5-[6-(2H-te... 2 0


External ID

Functional Category

Molecule Name

CFAMM00240687 CHEMBL410598 Bioactive alpha-ketooxazole, 11k
CFAMM00240743 CHEMBL257638 Bioactive AGN-PC-076E2D
CFAMM00240677 CHEMBL371831 Bioactive SureCN3962013
CFAMM00240699 CHEMBL35925 Bioactive SureCN3960103
CFAMM00240741 CHEMBL1812708 Bioactive 1-([1,3]oxazolo[4,5-b]pyridin-2-yl)decan-1-one
CFAMM00240728 CHEMBL464186 Bioactive AGN-PC-077RL8
CFAMM00240748 CHEMBL457924 Bioactive (Z)-1-([1,3]oxazolo[4,5-b]pyridin-2-yl)heptadec-8-en-1-one
CFAMM00240740 CHEMBL1812709 Bioactive 1-([1,3]oxazolo[4,5-b]pyridin-2-yl)heptan-1-one
CFAMM00240675 CHEMBL191424 Bioactive (Z)-2-methyl-1-([1,3]oxazolo[4,5-b]pyridin-2-yl)octadec-9-en-1-one
CFAMM00240738 CHEMBL1812706 Bioactive 1-([1,3]oxazolo[4,5-b]pyridin-2-yl)hexadecan-1-one
CFAMM00240737 CHEMBL1812707 Bioactive 1-([1,3]oxazolo[4,5-b]pyridin-2-yl)tetradecan-1-one
CFAMM00240706 CHEMBL179760 Bioactive AGN-PC-03S0QE
CFAMM00240753 CHEMBL182199 Bioactive AGN-PC-075CGI
CFAMM00240731 DNC004658 Investigative Drug 1-Oxazolo[4,5-b]pyridin-2-yl-6-phenyl-hexan-1-one
CFAMM00240730 DNC004659 Investigative Drug OL-92
CFAMM00240668 DNC004660 Investigative Drug 1-Oxazolo[4,5-b]pyridin-2-yl-octadec-9-yn-1-one
CFAMM00240692 DNC013503 Investigative Drug 1-(oxazolo[4,5-b]pyridin-2-yl)octan-1-one
CFAMM00240667 DNC013504 Investigative Drug 1-(oxazolo[4,5-b]pyridin-2-yl)dodecan-1-one
CFAMM00240666 DNC013502 Investigative Drug 1-(oxazolo[4,5-b]pyridin-2-yl)pentan-1-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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