CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1501
Family Name Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxazol-2-yl)octan-1-one Family
No. of Seeds 10 No. of Other Members 142
Family Centroid CFAMM00240764 Functional Category Investigative Drug with Natural Product
Superfamily Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxazol-2-yl)octan-1-one Superfamily
Class Class 2138

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Phospholipase A2, membrane associated Inhibitor Varespladib Fa... 37 190
Substance-P receptor Ligand R 673 Family 2 127
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-(b... 17 47
Fatty-acid amide hydrolase 1 Inhibitor (z)-1-(benzo[d]oxazol-2... 2 27
Fatty-acid amide hydrolase 1 Inhibitor 1-(oxazolo[4,5-b]pyridi... 19 34
Cytochrome P450 3A4 Inhibitor 3-(5-((methylthio)methyl)furan-2... 4 14
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-[5-(4-hydroxyphe... 4 36
Fatty-acid amide hydrolase 1 Inhibitor 7-phenyl-1-(5-phenyloxa... 3 3
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(furan-2-yl)oxazol... 2 1
Peroxisome proliferator-activated receptor delta ligand SureCN... 8 19
Muscarinic acetylcholine receptor M3 ligand [(3R)-1-[3-(1,3-be... 3 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 21
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 4 15
Histone deacetylase 1 and Histone deacetylase 2 inhibitor 7-[5... 1 2
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Fatty-acid amide hydrolase 1 inhibitor SureCN1471727 family 2 19
Cathepsin S and Cathepsin K inhibitor N-[(2S)-3-(1-methylcyclo... 2 0
Thromboxane-A synthase and Thromboxane A2 receptor ligand Sure... 5 37
Cytochrome P450 2C19 and Inositol monophosphatase 1 inhibitor ... 1 0
Inosine-5'-monophosphate dehydrogenase inhibitor SureCN1318237... 2 12
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 7
Histamine H3 receptor ligand SureCN2784306 family 5 3
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
Fatty-acid amide hydrolase 1 inhibitor [(2S)-6-phenoxy-1,2,3,4... 3 6
Fatty-acid amide hydrolase 1 and Liver carboxylesterase 1 inhi... 2 2
Sphingosine 1-phosphate receptor 1 ligand 6-[2-[6-propan-2-ylo... 1 1
Sphingosine 1-phosphate receptor 1 ligand 6-[2-[4-phenyl-3-(tr... 2 3
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 14 24
Sphingosine 1-phosphate receptor 1 ligand AGN-PC-00DWQL family 2 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 3
Fatty-acid amide hydrolase 1 inhibitor methyl 5-[2-(7-phenylhe... 2 4
Peroxisome proliferator-activated receptor alpha and Peroxisom... 5 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Peroxisome proliferator-activated receptor gamma and Peroxisom... 3 0
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 4jj ... 1 1
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 5a f... 2 1
Cathepsin S inhibitor (2S,4R)-4-(benzenesulfonyl)-N-[1-(1,3-be... 4 0
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 5
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 11 3
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 3
Fatty-acid amide hydrolase 1 inhibitor N-methyl-2-[3-[4-(pheno... 1 0
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-04UH7Y family 4 1
Leukotriene A-4 hydrolase inhibitor SureCN3030546 family 9 1
C-C chemokine receptor type 3 ligand SureCN6338683 family 1 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 3
Metabotropic glutamate receptor 5 ligand SureCN504754 family 5 4
Potassium voltage-gated channel subfamily H member 2 and ATP-s... 1 0
Metabotropic glutamate receptor 5 ligand 3-fluoro-5-(5-pyridin... 1 0
Fatty-acid amide hydrolase 1 inhibitor 7-phenyl-1-[5-[6-(2H-te... 2 0
Reverse transcriptase/RNaseH inhibitor 3-[2-(1-benzofuran-2-yl... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00240868 CHEMBL367009 Bioactive AGN-PC-007IGN
CFAMM00240831 CHEMBL175950 Bioactive SureCN3203324
CFAMM00240774 DNC004662 Investigative Drug 1-(5-Pyridin-2-yl-oxazol-2-yl)-octadec-9-yn-1-one
CFAMM00240773 DNC004661 Investigative Drug OL-135
CFAMM00240833 DNC013313 Investigative Drug 2-chloro-1-(5-(pyridin-2-yl)oxazol-2-yl)ethanone
CFAMM00240766 DNC013998 Investigative Drug 1-(5-(pyridin-2-yl)oxazol-2-yl)octadec-9-en-1-one
CFAMM00240832 DNC013312 Investigative Drug cyclopentyl(5-(pyridin-2-yl)oxazol-2-yl)methanone
CFAMM00240771 DNC013507 Investigative Drug 1-(5-(pyridin-2-yl)oxazol-2-yl)pentan-1-one
CFAMM00240764 DNC013508 Investigative Drug 1-(5-(pyridin-2-yl)oxazol-2-yl)octan-1-one
CFAMM00240763 DNC013509 Investigative Drug 1-(5-(pyridin-2-yl)oxazol-2-yl)dodecan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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