CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1508
Family Name Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-hydrazinylbenzenesulfonamide Family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00241091 Functional Category Investigative Drug
Superfamily Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Superfamily
Class Class 379

Cousin Family NamesSeedsMembers
Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 9 88
Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Family 19 117
Mannose-6-phosphate isomerase Inhibitor Sulfanilamide Family 4 8
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 3-chlo... 2 12
Carbonic anhydrase 2 Inhibitor 3-nitro-benzenesulfonamide Family 3 19
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-isot... 1 2
5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)pheny... 8 25
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor 3-((4-... 5 4
Prostaglandin G/H synthase 1 Inhibitor 4-amino-n-(2-chlorophen... 2 3
Gamma-aminobutyric acid receptor Ligand Toluene-1-diazonium-3-... 1 1
Carbonic anhydrase Inhibitor 4-amino-3-fluoro-5-iodobenzenesul... 1 0
Thyroid hormone receptor beta and Beta-lactamase ligand CHEMBL... 1 3
Prelamin-A/C and Cytochrome P450 3A4 inhibitor PHENYLHYDRAZINE... 1 11


External ID

Functional Category

Molecule Name

CFAMM00241089 DNC004676 Investigative Drug 2-hydrazinylbenzenesulfonamide
CFAMM00241091 DNC004672 Investigative Drug 4-hydrazinylbenzenesulfonamide
CFAMM00241090 DNC004673 Investigative Drug 3-Fluoro-4-hydrazino-benzenesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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