CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1512
Family Name Coagulation factor IX and Coagulation factor X Inhibitor Razaxaban Family
No. of Seeds 22 No. of Other Members 34
Family Centroid CFAMM00241218 Functional Category Investigative Drug
Superfamily Coagulation factor IX and Coagulation factor X Inhibitor Razaxaban Superfamily
Class Class 1228

Cousin Family NamesSeedsMembers
Coagulation factor X and Prothrombin Inhibitor BMS-740808 Family 64 8
Adenosine receptor A2b Ligand CVT-6694 Family 1 22
Adenosine receptor A2b Ligand CVT-7124 Family 14 64
Coagulation factor X and Prothrombin inhibitor 1-(3-amino-1,2-... 4 0
Coagulation factor X and Prothrombin inhibitor 2-(3-amino-1,2-... 5 3
Coagulation factor X inhibitor AGN-PC-046RMH family 5 0
Coagulation factor X and Prothrombin inhibitor 1-(4-methoxyphe... 8 0
Coagulation factor X and Prothrombin inhibitor 1-(3-amino-1,2-... 9 0
Coagulation factor X inhibitor 1-(3-amino-1,2-benzoxazol-5-yl)... 3 0
Coagulation factor X inhibitor SureCN5107814 family 6 0
Coagulation factor X inhibitor SureCN6603523 family 4 0
Coagulation factor X inhibitor AGN-PC-02YW2V family 1 0
Adenosine receptor A2b and Adenosine receptor A1 ligand 8-[1-[... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00241194 CHEMBL179964 Bioactive 2-(3-amino-1,2-benzoxazol-5-yl)-N-[2-fluoro-4-(1-methylimidazol-2-yl)phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
CFAMM00241207 CHEMBL384140 Bioactive 1-(3-amino-1,2-benzoxazol-5-yl)-6-[4-[2-[(dimethylamino)methyl]imidazol-1-yl]-2-fluorophenyl]-3-(trifluoromethyl)-4H-pyrazolo[4,3-d]pyrimidine-5,7-dione
CFAMM00241200 CHEMBL361846 Bioactive SureCN6198725
CFAMM00241241 CHEMBL179665 Bioactive 2-(3-amino-1,2-benzoxazol-5-yl)-N-[2-fluoro-4-[2-(pyrrolidin-1-ylmethyl)imidazol-1-yl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
CFAMM00241193 CHEMBL442292 Bioactive 1-[2-(3-amino-1,2-benzoxazol-5-yl)-5-(trifluoromethyl)pyrazol-3-yl]-2-[4-[2-[(dimethylamino)methyl]imidazol-1-yl]phenyl]ethanone
CFAMM00241231 CHEMBL398979 Bioactive SureCN6494926
CFAMM00241211 CHEMBL176157 Bioactive 2-(3-amino-1,2-benzoxazol-5-yl)-N-[2-carbamoyl-4-(2-methylimidazol-1-yl)phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
CFAMM00241191 CHEMBL367954 Bioactive SureCN6503086
CFAMM00241217 CHEMBL445391 Bioactive SureCN12589579
CFAMM00241245 CHEMBL368927 Bioactive AGN-PC-046QCA
CFAMM00241210 CHEMBL251158 Bioactive 1-(3-amino-1,2-benzoxazol-5-yl)-5-[5-[2-[(dimethylamino)methyl]imidazol-1-yl]-2,3-dihydroindole-1-carbonyl]pyrazole-3-carboxamide
CFAMM00241223 CHEMBL1270158 Bioactive SureCN5386162
CFAMM00241190 CHEMBL175449 Bioactive AGN-PC-006PWU
CFAMM00241216 CHEMBL176494 Bioactive SureCN5376245
CFAMM00241244 CHEMBL382559 Bioactive Aminobenzisoxazole 2s
CFAMM00241209 CHEMBL179410 Bioactive AGN-PC-009PNW
CFAMM00241215 CHEMBL251350 Bioactive SureCN6494300
CFAMM00241228 CHEMBL426957 Bioactive SureCN6197266
CFAMM00241243 CHEMBL355576 Bioactive SureCN5384478
CFAMM00241187 CHEMBL179213 Bioactive 2-(3-amino-1,2-benzoxazol-5-yl)-N-[2-methoxy-4-(2-methylimidazol-1-yl)phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
CFAMM00241218 DNC004682 Investigative Drug RAZAXABAN HYDROCHLORIDE
CFAMM00241222 DNC006431 Investigative Drug RAZAXABAN

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46415 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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