CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1514
Family Name Mitogen-activated protein kinase 14 Inhibitor 6-phenylsulfanyl-9h-purine Family
No. of Seeds 4 No. of Other Members 6
Family Centroid CFAMM00241277 Functional Category Investigative Drug
Superfamily Mitogen-activated protein kinase 14 Binder Superfamily
Class Class 2142

Cousin Family NamesSeedsMembers
Amiloride-sensitive sodium channel subunit alpha Ligand Triamt... 8 98
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2,6-di... 13 14
Adenosine receptor A3 Ligand 2,6-bis(4-chlorophenyl)-9h-purine... 4 12
Adenosine receptor A2a and Adenosine receptor A3 Ligand 5-buty... 3 18
Adenosine receptor A1 Ligand Phenyl-(9-phenyl-9h-purin-6-yl)-a... 7 12
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 1 9
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
Mitogen-activated protein kinase 14 Inhibitor 9-benzyl-6-pheny... 5 33
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55


External ID

Functional Category

Molecule Name

CFAMM00241270 DNC005314 Investigative Drug Cyclohexyl-(2-phenylsulfanyl-9H-purin-6-yl)-amine
CFAMM00241269 DNC004690 Investigative Drug 6-(4-Fluoro-phenylsulfanyl)-9H-purine
CFAMM00241268 DNC004697 Investigative Drug 6-Benzylsulfanyl-9H-purine
CFAMM00241277 DNC004685 Investigative Drug 6-Phenylsulfanyl-9H-purine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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