CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1520
Family Name Mitogen-activated protein kinase 14 Inhibitor 9-benzyl-6-phenylsulfanyl-9h-purine Family
No. of Seeds 5 No. of Other Members 33
Family Centroid CFAMM00241481 Functional Category Investigative Drug
Superfamily Mitogen-activated protein kinase 14 Binder Superfamily
Class Class 2142

Cousin Family NamesSeedsMembers
Toll-like receptor 7 Ligand Imiquimod Family 3 237
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
Equilibrative nucleoside/nucleobase transporter Inhibitor Nitr... 23 98
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2,6-di... 13 14
Adenosine receptor A2a and Adenosine receptor A3 Ligand 5-buty... 3 18
Adenosine receptor A1 Ligand Phenyl-(9-phenyl-9h-purin-6-yl)-a... 7 12
Mitogen-activated protein kinase 14 Inhibitor 6-phenylsulfanyl... 4 6
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
Metabotropic glutamate receptor 5 Ligand 4-(4-chlorophenylthio... 4 17
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 6 64
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Neuropeptide Y receptor type 5 ligand N-[[(1S,5R)-3-(1-phenyle... 5 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 10
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 5 27
Fatty-acid amide hydrolase 1 inhibitor 5-[5-(4-chlorophenyl)su... 2 4
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Adenosine receptor A2b and Adenosine receptor A3 ligand 3-[5-(... 4 2
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 7
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 4 5
Transient receptor potential cation channel subfamily V member... 1 0
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor AGN-P... 1 0
Equilibrative nucleoside transporter 1 inhibitor 2-[[6-[(4-nit... 1 10


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00241475 DNC004864 Investigative Drug 9-Benzyl-6-(4-nitro-benzylsulfanyl)-9H-purine
CFAMM00241481 DNC004736 Investigative Drug 9-Benzyl-6-phenylsulfanyl-9H-purine
CFAMM00241471 DNC005256 Investigative Drug 6-(4-Nitro-benzylsulfanyl)-9-phenethyl-9H-purine
CFAMM00241451 DNC004742 Investigative Drug 9-Benzyl-6-(4-fluoro-phenylsulfanyl)-9H-purine
CFAMM00241450 DNC004743 Investigative Drug 9-(4-Fluoro-benzyl)-6-phenylsulfanyl-9H-purine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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