CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1523
Family Name DNA-dependent protein kinase catalytic subunit Inhibitor 4-morpholin-4-yl-chromen-2-one Family
No. of Seeds 7 No. of Other Members 54
Family Centroid CFAMM00241509 Functional Category Investigative Drug with Natural Product
Superfamily DNA-dependent protein kinase catalytic subunit Binder Superfamily
Class Class 2143

Cousin Family NamesSeedsMembers
D(4) dopamine receptor Ligand PD-165167 Family 2 96
Acolbifene family 10 115
DNA-dependent protein kinase catalytic subunit Inhibitor 6-chl... 2 9
Adenosine receptor A3 and Muscarinic acetylcholine receptor M2... 4 31
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-amino-2h-chromen... 2 3
Amine oxidase [flavin-containing] B Inhibitor N-methyl-n-pheny... 6 25
Amine oxidase [flavin-containing] B Inhibitor N-isobutyl-2-oxo... 4 8
5-hydroxytryptamine receptor 7 Ligand (r)-8-phenyl-n,n-dipropy... 9 14
Cytochrome P450 2D6 Inhibitor 4-methylaminomethyl-7-methoxycou... 3 80
Acetylcholinesterase Inhibitor 6-methyl-4-(4-phenylpiperazin-1... 6 622
Mu-type opioid receptor and Sigma non-opioid intracellular rec... 10 20
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-ben... 5 334
Shiga toxin 1 variant B subunit and Shiga toxin 1 variant A su... 1 117
D(2) dopamine receptor and D(1A) dopamine receptor ligand ISOM... 2 5
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-[(4... 3 53
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-ben... 3 2
Estrogen receptor ligand 4-(dodecylamino)-3-[(2-methylphenyl)m... 1 2
C-C chemokine receptor type 4 ligand AGN-PC-07AKPI family 1 5
DNA-(apurinic or apyrimidinic site) lyase and Inositol monopho... 1 22


External ID

Functional Category

Molecule Name

CFAMM00241509 DNC004764 Investigative Drug 4-Morpholin-4-yl-chromen-2-one
CFAMM00241508 DNC004765 Investigative Drug 4-Piperidin-1-yl-chromen-2-one
CFAMM00241506 DNC004768 Investigative Drug 6-Methoxy-4-morpholin-4-yl-chromen-2-one
CFAMM00241505 DNC004769 Investigative Drug 7-Methoxy-4-morpholin-4-yl-chromen-2-one
CFAMM00241511 DNC004766 Investigative Drug 6-Methyl-4-morpholin-4-yl-chromen-2-one
CFAMM00241510 DNC004767 Investigative Drug 8-Methyl-4-morpholin-4-yl-chromen-2-one
CFAMM00241545 DNC004770 Investigative Drug 8-Methoxy-4-morpholin-4-yl-chromen-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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