CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1532
Family Name Histone Deacetylase 8 Inhibitor 6-(2-mercaptoacetamido)-n-phenylhexanamide Family
No. of Seeds 4 No. of Other Members 8
Family Centroid CFAMM00241707 Functional Category Investigative Drug
Superfamily Histone deacetylase 2 and Histone deacetylase 1 Binder Superfamily
Class Class 1971

Cousin Family NamesSeedsMembers
Sodium channel Ligand xylidine derivative Mepivacaine Family 10 114
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Family 19 117
Mannose-6-phosphate isomerase Inhibitor Sulfanilamide Family 4 8
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Tyrosine-protein phosphatase non-receptor type 1 Ligand [[4-(a... 1 7
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 6-(2... 1 1
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-morp... 6 81
Transient receptor potential cation channel subfamily V member... 6 33
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 1 1
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 45
Acetylcholinesterase Inhibitor (3-hydroxy-2-methyl-phenyl)-tri... 4 25
Tyrosinase Inhibitor S-2-(o-toluidino)-2-oxoethyl Carbamothioa... 1 1
Histone Deacetylase 8 Inhibitor S-2,9-dioxo-9-(phenylamino)non... 1 0
Prothrombin and Plasminogen inhibitor [(1R)-5-amino-1-[[2-[N-(... 1 0
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-amin... 2 2
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-[car... 3 3
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-(met... 4 1
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
Matrix metalloproteinase-9 and Stromelysin-1 inhibitor N-[(2S)... 1 1
Cathepsin K and Cathepsin L1 inhibitor 1-[(2S)-1-[[cyano(methy... 2 1
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 3
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor ST510... 7 3
Peptide deformylase inhibitor AGN-PC-073KFH family 6 8
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-amin... 1 0
Cathepsin K inhibitor AGN-PC-075F1H family 2 0
Proteasome subunit beta type-5 and Proteasome subunit beta typ... 1 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00241701 DNC005609 Investigative Drug N-(2-Mercapto-ethyl)-N'-phenyl-oxalamide
CFAMM00241710 DNC005610 Investigative Drug N-(2-Mercapto-ethyl)-N'-phenyl-succinamide
CFAMM00241709 DNC004805 Investigative Drug 5-Mercapto-pentanoic acid phenylamide
CFAMM00241707 DNC013517 Investigative Drug 6-(2-mercaptoacetamido)-N-phenylhexanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27768 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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