CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1537
Family Name Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-mercapto-heptanoic Acid Benzothiazol-2-ylamide Family
No. of Seeds 2 No. of Other Members 45
Family Centroid CFAMM00241895 Functional Category Investigative Drug with Natural Product
Superfamily Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-mercapto-heptanoic Acid Benzothiazol-2-ylamide Superfamily
Class Class 2148

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor RWJ-50353 Family 11 95
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
C-C chemokine receptor type 4 Ligand N-(naphthalen-1-yl)-4-neo... 5 78
C-C chemokine receptor type 4 Ligand 4-tert-butyl-n-o-tolylthi... 4 7
Metabotropic glutamate receptor 5 Ligand 3-chloro-n-(4-methylt... 2 12
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor 7-me... 3 14
Nitric oxide synthase, brain and Nitric oxide synthase, endoth... 2 11
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 4 3
Adenosine receptor A1 Ligand N-(4-phenyl-thiazol-2-yl)-benzami... 5 2
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-264... 6 32
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(5-b... 3 9
Reverse transcriptase Inhibitor 1-benzothiazol-2-yl-3-phenethy... 2 19
Adenosine receptor A1 Ligand 4-nitro-n-(4-phenyl-thiazol-2-yl)... 2 38
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 2 5
Histone deacetylase 1 and Histone deacetylase 2 inhibitor 7-[4... 3 0
Cellular tumor antigen p53 and Protein-cysteine N-palmitoyltra... 1 7
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-phenyl-1,3-t... 3 4
Suppressor of tumorigenicity 14 protein and Serine protease he... 6 0
Cathepsin K and Cathepsin L1 inhibitor (2R)-N-(cyanomethyl)-4-... 2 1
Cholinesterase and Acetylcholinesterase inhibitor 3-[ethyl-[3-... 6 9
Bifunctional epoxide hydrolase 2 inhibitor 1-(1-adamantyl)-3-(... 1 0
Histone deacetylase 1 inhibitor N',N'-bis[2-(1,3-benzothiazol-... 2 0
Neuropeptide Y receptor type 5 ligand 2-(dimethylamino)-1-[4-[... 10 5
Neuropeptide Y receptor type 5 ligand 1-[4-[[(9-fluoro-5,6-dih... 11 0
Integrin beta-3 and Integrin alpha-IIb inhibitor 4-[[4-(4-carb... 4 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Membrane primary amine oxidase inhibitor N-[4-[2-[4-(diaminome... 5 0
Beta-lactamase and Microtubule-associated protein tau inhibito... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00241836 CHEMBL1095276 Bioactive AC1LG8Y5
CFAMM00241895 DNC004813 Investigative Drug 7-Mercapto-heptanoic acid benzothiazol-2-ylamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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