CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1544
Family Name Cytochrome P450 3A4 Inhibitor 3-(5-((methylthio)methyl)furan-2-yl)pyridine Family
No. of Seeds 4 No. of Other Members 14
Family Centroid CFAMM00242124 Functional Category Investigative Drug with Human Metabolite
Superfamily Cytochrome P450 3A4 Inhibitor 3-(5-((methylthio)methyl)furan-2-yl)pyridine Superfamily
Class Class 656

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand Sun N4057 Family 2 86
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxaz... 10 142
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 3 44
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
Lanosterol synthase inhibitor (4-bromophenyl)-[6-[6-[methyl(pr... 1 1
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 4 15
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 7
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
Fatty-acid amide hydrolase 1 and Liver carboxylesterase 1 inhi... 2 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 3
CGMP-dependent protein kinase inhibitor AGN-PC-075IHL family 2 8
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 3
Mu-type opioid receptor ligand N-[(5-methylfuran-2-yl)methyl]-... 1 0
Reverse transcriptase/RNaseH inhibitor CHEMBL254438 family 1 0
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 2 i... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00242126 DNC006935 Investigative Drug 3-(5-[1,3]dithiolan-2-yl-furan-2-yl)pyridine
CFAMM00242134 DNC004861 Investigative Drug (5-(pyridin-3-yl)furan-2-yl)methanamine
CFAMM00242125 DNC006937 Investigative Drug (5-pyridin-3-yl-furan-2-yl)methanethiol
CFAMM00242124 DNC006936 Investigative Drug 3-(5-((methylthio)methyl)furan-2-yl)pyridine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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