CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1550
Family Name Extracellular calcium-sensing receptor and Potassium voltage-gated channel subfamily H member 2 Ligand NPS-2143 Family
No. of Seeds 3 No. of Other Members 11
Family Centroid CFAMM00242578 Functional Category Investigative Drug
Superfamily Extracellular calcium-sensing receptor and Potassium voltage-gated channel subfamily H member 2 Ligand NPS-2143 Superfamily
Class Class 80

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand naphthol derivative Propranolo... 11 218
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Beta adrenergic receptor Ligand Levobunolol Family 6 133
Beta-1 adrenergic receptor Ligand Esmolol Family 5 39
Beta-1 adrenergic receptor Ligand Metoprolol Family 29 90
Beta adrenergic receptor Ligand Metipranolol Family 5 1
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Beta-1 adrenergic receptor Ligand Nebivolol Family 5 22
5-hydroxytryptamine receptor 2A Ligand Sarpogrelate Family 2 15
Extracellular calcium-sensing receptor Ligand Ronacaleret Family 2 9
Beta-3 adrenergic receptor Ligand Amibegron Family 8 46
5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 2 5
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 5 14
5-hydroxytryptamine receptor 2A Ligand C-(9h-xanthen-9-yl)-met... 3 5
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 6 5
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 2 11
Extracellular calcium-sensing receptor and Sodium-dependent no... 2 2
D(4) dopamine receptor and D(3) dopamine receptor ligand N-[2-... 6 15
5-hydroxytryptamine receptor 1A ligand oxalic acid;(1R,5S)-5-[... 2 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 0
Sodium-dependent noradrenaline transporter and Cytochrome P450... 11 2
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 0
Extracellular calcium-sensing receptor ligand SureCN4609584 fa... 7 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00242579 CHEMBL2112075 Bioactive NPS 2143 hydrochloride
CFAMM00242586 CHEMBL382741 Bioactive 2-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile
CFAMM00242578 DNC004878 Investigative Drug NPS-2143

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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