CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1561
Family Name Extracellular calcium-sensing receptor Ligand 2-furan-2-yl-3-phenethyl-3h-quinazolin-4-one Family
No. of Seeds 4 No. of Other Members 119
Family Centroid CFAMM00242832 Functional Category Investigative Drug with Natural Product
Superfamily Extracellular calcium-sensing receptor and Induced myeloid leukemia cell differentiation protein Mcl-1 Binder Superfamily
Class Class 2156

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-methoxy-phenyl)-... 1 3
Poly [ADP-ribose] polymerase 1 Inhibitor 8-methoxy-2-phenyl-3h... 4 6
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Prelamin-A/C and Survival motor neuron protein inhibitor CHEMB... 1 7
Vasopressin V1b receptor ligand AGN-PC-09QGT9 family 4 123
Vasopressin V1b receptor ligand AGN-PC-00HJ2S family 4 6
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 2
C-X-C chemokine receptor type 3 ligand N-(2-ethoxyethyl)-N-[(1... 1 1
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 10
Ghrelin/growth hormone secretagogue receptor and Cytochrome P4... 5 20
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Histamine H3 receptor and Potassium voltage-gated channel subf... 16 2
Histamine H3 receptor ligand AGN-PC-03Z8FM family 5 0
Histamine H3 receptor ligand AGN-PC-00AE5Q family 13 13
Histamine H3 receptor and Potassium voltage-gated channel subf... 28 30
Histamine H3 receptor ligand AGN-PC-03Z8HJ family 4 1
5-hydroxytryptamine receptor 7 ligand 4-[4-(2-ethoxyphenyl)pip... 2 5
Multidrug resistance protein 1B and Multidrug resistance-assoc... 1 4
Nicotinamide phosphoribosyltransferase inhibitor N-(1,3-benzod... 1 0
Adenosine receptor A2a and Amine oxidase [flavin-containing] B... 4 0
Beta-lactamase and 4'-phosphopantetheinyl transferase ffp inhi... 1 0
Tubulin beta-4A chain and Tubulin beta-2B chain inhibitor 6-[(... 2 0


External ID

Functional Category

Molecule Name

CFAMM00242815 CHEMBL598688 Bioactive GNF-Pf-724
CFAMM00242973 CHEMBL557214 Bioactive 2-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]-3-(tritritiomethyl)quinazolin-4-one
CFAMM00242841 CHEMBL488248 Bioactive AGN-PC-00C0ZP
CFAMM00242832 DNC004905 Investigative Drug 2-Furan-2-yl-3-phenethyl-3H-quinazolin-4-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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