CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1562
Family Name Reverse transcriptase Inhibitor 2-amino-6-(naphthalene-1-sulfonyl)-benzonitrile Family
No. of Seeds 3 No. of Other Members 6
Family Centroid CFAMM00243009 Functional Category Investigative Drug
Superfamily Reverse transcriptase Binder Superfamily
Class Class 1052

Cousin Family NamesSeedsMembers
Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 9 88
UDP-N-acetylglucosamine 1-carboxyvinyltransferase Inhibitor 1-... 1 6
5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)pheny... 8 25
Reverse transcriptase Inhibitor 2-amino-6-(2-cyano-benzenesulf... 16 2
Phosphoribosylaminoimidazolecarboxamide formyltransferase Inhi... 3 8
Gamma-aminobutyric acid receptor Ligand 7-diazonium-naphthalen... 2 4
Capsid scaffolding protein inhibitor 1,1,1-trifluoro-N-[5-[(E)... 3 1
5-hydroxytryptamine receptor 6 ligand AGN-PC-014RDG family 1 3
Kinesin-like protein KIF11 inhibitor SureCN4766565 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00243004 DNC004907 Investigative Drug 4-(Naphthalene-1-sulfonyl)-phenylamine
CFAMM00243010 DNC012022 Investigative Drug 2-Amino-6-(naphthalene-2-sulfonyl)-benzonitrile
CFAMM00243009 DNC012056 Investigative Drug 2-Amino-6-(naphthalene-1-sulfonyl)-benzonitrile

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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