CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1563
Family Name Extracellular calcium-sensing receptor Ligand 3-phenethyl-2-phenyl-3h-quinazolin-4-one Family
No. of Seeds 3 No. of Other Members 137
Family Centroid CFAMM00243051 Functional Category Investigative Drug with Natural Product
Superfamily Extracellular calcium-sensing receptor Ligand 3-phenethyl-2-phenyl-3h-quinazolin-4-one Superfamily
Class Class 2030

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
5-hydroxytryptamine 2 receptor Ligand Ketanserin Family 10 253
Kinesin-like protein KIF11 Inhibitor Ispinesib Family 4 37
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
K-604 family 4 71
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-amino-phenyl)-8-... 4 35
Poly [ADP-ribose] polymerase 1 Inhibitor 5-chloro-2-methyl-3h-... 1 1
Peptide deformylase, mitochondrial Inhibitor 2-allylthio-3-ben... 3 17
Poly [ADP-ribose] polymerase 1 Inhibitor 8-methyl-2-(4-nitro-p... 1 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
Amine oxidase [flavin-containing] B Inhibitor 2-hydrazino-3-me... 1 6
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 53
Ghrelin/growth hormone secretagogue receptor ligand AGN-PC-00A... 7 27
Coagulation factor VII inhibitor 3-amino-N-[(2R)-butan-2-yl]-5... 2 7
Urokinase plasminogen activator surface receptor ligand 5,12-d... 1 0
Dipeptidyl peptidase 4 and Cytochrome P450 3A4 inhibitor SureC... 3 8
Histone deacetylase 6 and Histone deacetylase 8 inhibitor (E)-... 2 8
Poly [ADP-ribose] polymerase 1 inhibitor 8-chloro-2-[(3S)-3-(4... 2 8
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 3 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 2
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 1
Acetylcholinesterase and Cholinesterase inhibitor N-[4-[(E)-(6... 1 1
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor 4-oxo... 3 1
C-X-C chemokine receptor type 3 ligand N-[2-(dimethylamino)eth... 3 4
Collagenase 3 inhibitor 4-[[4-oxo-6-(3-phenylprop-1-ynyl)quina... 1 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 0
Delta-type opioid receptor ligand SureCN7549631 family 6 3
Delta-type opioid receptor ligand SureCN7542096 family 1 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
Telomerase reverse transcriptase inhibitor AGN-PC-07ZBGW family 2 0
Niemann-Pick C1 protein and Ras-related protein Rab-9A inhibit... 1 3
Poly [ADP-ribose] polymerase 1 inhibitor 8-amino-1H-quinazolin... 1 2
Prostaglandin E synthase inhibitor 2-chloro-N-[3-[[4-(3-chloro... 5 0
Beta-secretase 1 inhibitor 3-(2-Amino-6-Benzoylquinazolin-3(4h... 1 0
quinazolin-4-one NP Megxm0 000086 Family 3 0
Putative NP ZINC06549259 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00243156 CHEMBL251027 Bioactive SureCN7704600
CFAMM00243167 DNC005174 Investigative Drug 2-(3-Piperidin-1-yl-propyl)-3H-quinazolin-4-one
CFAMM00243051 DNC004909 Investigative Drug 3-Phenethyl-2-phenyl-3H-quinazolin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27639 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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