CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1593
Family Name Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-morpholin-4-yl-n-(4-sulfamoyl-phenyl)-acetamide Family
No. of Seeds 6 No. of Other Members 81
Family Centroid CFAMM00244446 Functional Category Investigative Drug
Superfamily Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-morpholin-4-yl-n-(4-sulfamoyl-phenyl)-acetamide Superfamily
Class Class 2170

Cousin Family NamesSeedsMembers
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Family 19 117
Mannose-6-phosphate isomerase Inhibitor Sulfoxone Family 3 20
Mannose-6-phosphate isomerase Inhibitor Sulfanilamide Family 4 8
5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-(4-s... 12 92
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Histone Deacetylase 8 Inhibitor 6-(2-mercaptoacetamido)-n-phen... 4 8
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-[2-(... 5 72
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 3-(3-p... 7 17
5-hydroxytryptamine receptor 6 Ligand 4-(4-benzenesulfonamidop... 4 5
5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)pheny... 8 25
Carbonic anhydrase 2 and Prostaglandin G/H synthase 2 Inhibito... 1 1
Fructose-1,6-bisphosphatase 1 Inhibitor 1-(4-aminophenylsulfon... 2 1
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor 3-((4-... 5 4
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-158324 Family 1 1
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Thiour... 3 14
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-amin... 2 2
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-(met... 4 4
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-[car... 3 3
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-(met... 4 1
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 17 16
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 2 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 1
Protein-glutamine gamma-glutamyltransferase 2 and Coagulation ... 1 0
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 4 8
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 2,3,5,... 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 7 5
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-[[2-... 1 2
Disintegrin and metalloproteinase domain-containing protein 17... 1 0
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-[bis... 3 6
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor ST510... 7 3
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-[bis... 2 4
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-[2-[... 1 4
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-amin... 1 0
Carbonic anhydrase and Carbonic anhydrase 2 inhibitor AGN-PC-0... 2 0
Protein-glutamine gamma-glutamyltransferase 2 and Coagulation ... 3 2
Coagulation factor XIII A chain and Protein-glutamine gamma-gl... 2 3
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor AGN-PC... 1 0
Aldo-keto reductase family 1 member C3 inhibitor 2-[3-(3,4-dih... 1 0
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor N-(4-... 1 0
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor N-(4-... 2 0
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00244432 CHEMBL34016 Bioactive ST51002830
CFAMM00244452 CHEMBL183775 Bioactive AC1LC1D9
CFAMM00244442 CHEMBL123827 Bioactive 2-amino-N-[2-oxo-2-[4-[(4-sulfamoylphenyl)sulfamoyl]anilino]ethyl]acetamide
CFAMM00244446 DNC004968 Investigative Drug 2-Morpholin-4-yl-N-(4-sulfamoyl-phenyl)-acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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