CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1596
Family Name Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Alpha-msh Family
No. of Seeds 4 No. of Other Members 18
Family Centroid CFAMM00244481 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Somatrem Superfamily
Class Class 767

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Captopril Family 13 27
Bacterial outer membrane inhibitor polymyxin Colistin Family 26 160
Glutamine receptor Ligand L-alanyl-l-glutamine Family 3 101
Synaptic vesicle glycoprotein 2A Inhibitor Brivaracetam Family 9 46
Hepatitis C Vaccine family 1 5
D-alanyl-D-alanine carboxypeptidase Inhibitor Glycyl-l-alpha-a... 5 89
Farnesyltransferase beta subunit, putative and Protein farnesy... 3 29
Integrin alpha-V and Integrin beta-3 Inhibitor Cyclo-[-arg-gly... 6 11
Sodium/glucose cotransporter 1 Inhibitor Qcpac Family 4 7
Sodium/glucose cotransporter 1 Inhibitor Qspac Family 3 8
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 6 3
Alpha-galactosidase A Inhibitor AT1001 Family 1 0
Angiotensin-converting enzyme inhibitor SureCN10957020 family 2 1
Angiotensin-converting enzyme inhibitor AC1L5A5N family 1 1
Endothelin-converting enzyme 1 and Renin inhibitor tert-butyl ... 5 5
Cathepsin L1 and Cathepsin B inhibitor L-Arginine, N2-(N-(N-ac... 1 7
Nucleotide-binding oligomerization domain-containing protein 1... 14 7
Proprotein convertase subtilisin/kexin type 6 and Furin inhibi... 3 11
Angiotensin-converting enzyme inhibitor 1-[2-[[carboxy-[1-(car... 2 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor Gl... 1 0
Caspase-1 inhibitor (2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-methy... 1 9
Beta-lactamase and DNA-(apurinic or apyrimidinic site) lyase i... 1 8
NAD-dependent protein deacetylase sirtuin-1 and NAD-dependent ... 4 0
Renin inhibitor (2S)-1-[(2R)-4-(hydroxyamino)-2-methyl-4-oxobu... 2 0
Amino Acids and Derivatives Metabolite 2-Methylbutyrylglycine ... 2 0
Peptides Metabolite Valyl-Hydroxyproline Family 1 1
Peptides Metabolite L-prolyl-L-glycine Family 1 3
NP (s)-2-(1-((s)-2-amino-3-methylbutanoyl)piperidine-4-carboxa... 10 0
Putative NP ZINC04060955 Family 10 2
2-[(2-azaniumylacetyl)amino]pentanoate NP 2-(2-aminoacetamido)... 3 2
carboxylate NP (r)-tert-butyl 2-(((r)-1-((2-methoxy-2-oxoethyl... 2 3
[(2R)-1-[(2-ethoxy-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00244509 CHEMBL78340 Bioactive (2S)-1-[(2S)-2-[(1-carboxy-4-methylpentyl)amino]propanoyl]pyrrolidine-2-carboxylic acid
CFAMM00244488 CHEMBL108606 Bioactive AGN-PC-02TOIQ
CFAMM00244511 DNC013488 Investigative Drug DIPROTIN A
CFAMM00244481 DNC004973 Investigative Drug Alpha-MSH

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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