CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 5-hydroxytryptamine receptor 2A Ligand Fananserin Family
No. of Seeds 13 No. of Other Members 49
Family Centroid CFAMM00174508 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 2A Ligand Fananserin Superfamily
Class Class 1359

Cousin Family NamesSeedsMembers
Carbonic anhydrase 2 Inhibitor Dansylamide Family 1 9
Interstitial collagenase and Neutrophil collagenase inhibitor ... 3 9
5-hydroxytryptamine receptor 6 ligand 1-(5-chloronaphthalen-1-... 1 5
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 9 26
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-chl... 2 16
5-hydroxytryptamine receptor 6 ligand AGN-PC-075CMN family 2 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[[4... 7 11
Growth hormone secretagogue receptor type 1 ligand SureCN47963... 3 3
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-met... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor aryls... 2 3
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 3 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
5-hydroxytryptamine receptor 6 ligand AGN-PC-014RDG family 1 3
Cannabinoid receptor 1 ligand N-[[(3R,6S)-1-(4-chlorophenyl)-6... 1 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 0
Phenylethanolamine N-methyltransferase and Alpha-2B adrenergic... 2 5
Bifunctional epoxide hydrolase 2 inhibitor SureCN12962025 family 1 1


External ID

Functional Category

Molecule Name

CFAMM00174464 CHEMBL83035 Bioactive AGN-PC-001VSU
CFAMM00174457 CHEMBL83780 Bioactive AGN-PC-001VSW
CFAMM00174481 CHEMBL84465 Bioactive SureCN9757611
CFAMM00174474 CHEMBL83975 Bioactive SureCN9757364
CFAMM00174487 CHEMBL418929 Bioactive AGN-PC-001VSR
CFAMM00174479 CHEMBL440134 Bioactive SureCN9757173
CFAMM00174514 CHEMBL82651 Bioactive AGN-PC-001VSQ
CFAMM00174478 CHEMBL416544 Bioactive CHEMBL416544
CFAMM00174493 CHEMBL82229 Bioactive CHEMBL82229
CFAMM00174458 CHEMBL83787 Bioactive AGN-PC-001VSN
CFAMM00174499 CHEMBL310105 Bioactive AGN-PC-001VSZ
CFAMM00174512 CHEMBL82826 Bioactive CHEMBL82826
CFAMM00174508 DPR000043 Investigative Drug Fananserin

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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