CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name DNA polymerase catalytic subunit Inhibitor Aphidicolin Family
No. of Seeds 2 No. of Other Members 38
Family Centroid CFAMM00182433 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily DNA polymerase catalytic subunit Inhibitor Aphidicolin Superfamily
Class Class 1439

Cousin Family NamesSeedsMembers
Androgen receptor ligand Anabolic steroid Dromostanolone Family 9 408
Biliverdin reductase A and Solute carrier Family 23 member 2 i... 9 112
Sterol 24-C-methyltransferase Inhibitor 24-thiacycloartanol Fa... 1 0
DNA topoisomerase 2-beta Inhibitor Lupeol Family 2 23
Prelamin-A/C and Ferritin light chain inhibitor CHEMBL1524039 ... 3 61
Prenol Lipids Metabolite gamma-Taraxastane-3,20-diol Family 1 11
Prenol Lipids Metabolite 3-Epipapyriferic acid Family 1 0


External ID

Functional Category

Molecule Name

CFAMM00182458 DNC012924 Investigative Drug haloxysterol D
CFAMM00182433 DNC000238 Investigative Drug Aphidicolin

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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