CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1600
Family Name Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor Ligand SK&F-64139 Family
No. of Seeds 6 No. of Other Members 7
Family Centroid CFAMM00244586 Functional Category Investigative Drug
Superfamily Dopamine reuptake and Noradrenergic re-uptake Inhibitor Dov 21947 Superfamily
Class Class 48

Cousin Family NamesSeedsMembers
Serotonin re-uptake inhibitor tetralin derivative Sertraline f... 12 118
Adrenergic neuron Inhibitor guanidine isoquinoline analog Debr... 2 44
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Sibu... 7 127
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Dov 21... 16 89
Dopamine reuptake and Noradrenergic re-uptake Inhibitor GSK372... 7 61
5-hydroxytryptamine receptor 2C Ligand Lorcaserin Family 8 38
Zicronapine family 43 62
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 3 7
Dipeptidyl peptidase 4 Inhibitor C-(2'-chloro-biphenyl-2-yl)-m... 2 5
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 6 24
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 1
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Sigma non-opioid intracellular receptor 1 ligand NCI60_038428 ... 5 9
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 18 4
Sigma non-opioid intracellular receptor 1 ligand 1-[2-(3,4-dic... 8 4
Sodium-dependent serotonin transporter and Sodium-dependent do... 5 6
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 0
Transporter and Sodium-dependent dopamine transporter inhibito... 3 0
Sodium-dependent dopamine transporter inhibitor [3-(4-chloroph... 1 1
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 3
Sodium-dependent dopamine transporter and Sodium-dependent nor... 3 1
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 0
Sigma non-opioid intracellular receptor 1 ligand NCI60_039912 ... 2 0
Sodium-dependent dopamine transporter and Muscarinic acetylcho... 2 6
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 0
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 10
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00244589 CHEMBL194469 Bioactive SureCN4692003
CFAMM00244586 DNC004983 Investigative Drug SK&F-64139

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27744 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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