CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1602
Family Name Alpha-2A adrenergic receptor Ligand 7-nitro-1,2,3,4-tetrahydro-isoquinoline Family
No. of Seeds 6 No. of Other Members 31
Family Centroid CFAMM00244669 Functional Category Investigative Drug
Superfamily Alpha-2A adrenergic receptor Ligand 7-nitro-1,2,3,4-tetrahydro-isoquinoline Superfamily
Class Class 2177

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 8 32
Amyloid beta A4 protein Inhibitor 1,6-bis(4'-nitrophenyl)-hexa... 3 60
Histamine H3 receptor Ligand (r)-1-(4-nitrophenethyl)-2-methyl... 16 38
Nitric oxide synthase, brain Inhibitor N*1*-(5-methyl-2-nitro-... 1 19
Sigma non-opioid intracellular receptor 1 ligand 1-[(3-nitroph... 4 2
5-hydroxytryptamine receptor 7 ligand 1-[2-(4-nitrophenyl)phen... 1 0
Androgen receptor and Cathepsin B ligand 1-(4-nitronaphthalen-... 1 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 0
Phenylethanolamine N-methyltransferase and Alpha-2A adrenergic... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00244665 CHEMBL190826 Bioactive SureCN5685749
CFAMM00244656 CHEMBL535600 Bioactive SureCN4405952
CFAMM00244675 CHEMBL191174 Bioactive SureCN5685555
CFAMM00244646 CHEMBL197998 Bioactive SureCN2062764
CFAMM00244670 DNC004986 Investigative Drug 3-Methyl-7-nitro-1,2,3,4-tetrahydro-isoquinoline
CFAMM00244669 DNC004985 Investigative Drug 7-Nitro-1,2,3,4-tetrahydro-isoquinoline

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26845 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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