CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID161
Family Name NMDA receptor Ligand Aptiganel Hcl Family
No. of Seeds 2 No. of Other Members 82
Family Centroid CFAMM00182515 Functional Category Investigative Drug
Superfamily NMDA receptor Ligand Aptiganel Hcl Superfamily
Class Class 1440

Cousin Family NamesSeedsMembers
Sodium channel Ligand iminostilbene derivative (tricyclic stru... 2 46
Histamine H1 receptor Ligand Epinastine Family 2 26
Histamine H1 receptor Ligand Antazoline Family 5 57
D(2) dopamine receptor Ligand Nomifensine Family 6 100
Urokinase-type plasminogen activator Inhibitor N-(1-adamantyl)... 2 15
5-hydroxytryptamine receptor 5A Ligand N,4-dimethyl-3,4-dihydr... 8 51
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 14 78
Progesterone receptor Ligand 2,2,4-trimethyl-6-phenyl-1,2-dihy... 5 82
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
Androgen receptor Ligand YM-175735 Family 30 129
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 7 134
Dipeptidyl peptidase 4 Inhibitor (3s,4r)-3-butyl-1-phenylpiper... 2 40
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Voltage-dependent L-type calcium channel subunit alpha-1D Liga... 1 11
DNA topoisomerase Inhibitor 6-(naphthalen-2-ylamino)-1h-pyrimi... 2 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Inosine-5'-monophosphate dehydrogenase inhibitor 1-[2-[3-[(E)-... 3 6
Bifunctional epoxide hydrolase 2 inhibitor 1-(2-adamantyl)-3-(... 2 4
Testosterone 17-beta-dehydrogenase 3 inhibitor SureCN4802053 f... 2 2
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 1-(3,5... 2 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
Sigma non-opioid intracellular receptor 1 and Glutamate recept... 3 2
Sigma non-opioid intracellular receptor 1 and Glutamate recept... 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 0
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 7 2
Sodium channel protein type 2 subunit alpha and Glutamate rece... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00182572 CHEMBL38936 Bioactive AGN-PC-07Z9RG
CFAMM00182515 DNC000246 Investigative Drug Aptiganel HCl

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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