CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1619
Family Name 5-hydroxytryptamine receptor 6 Ligand [2-(3h-indol-1-yl)-ethyl]-dimethyl-amine Family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00244890 Functional Category Investigative Drug with Natural Product
Superfamily 5-hydroxytryptamine receptor 6 and Potassium voltage-gated channel subfamily A member 3 Binder Superfamily
Class Class 22

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake inhibitor Dibenzazepine Imipramine Family 8 178
Calmodulin Inhibitor Aprindine Family 1 4
Histamine H1 receptor Ligand Antazoline Family 5 57
Potassium voltage-gated channel subfamily A member 3 Ligand CP... 4 26
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor 1,3,... 3 4
Progesterone receptor Ligand 2,2,4-trimethyl-6-phenyl-1,2-dihy... 5 82
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
Acetylcholinesterase Inhibitor Bw-28c51 Family 3 8
Dipeptidyl peptidase 4 Inhibitor (3s,4r)-3-butyl-1-phenylpiper... 2 40
Histamine H3 receptor Ligand (r)-1-(4-nitrophenethyl)-2-methyl... 16 38
Cholinesterase Inhibitor (-)-debromoflustramine B Family 2 14
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 42
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 18
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 7 27
Sigma non-opioid intracellular receptor 1 ligand 1-[4-[1-adama... 4 23
Nitric oxide synthase, brain and Nitric oxide synthase, induci... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00244891 DNC005037 Investigative Drug [2-(3-Benzyl-3H-indol-1-yl)-ethyl]-dimethyl-amine
CFAMM00244890 DNC005036 Investigative Drug [2-(3H-Indol-1-yl)-ethyl]-dimethyl-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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