CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1621
Family Name Fatty acid-binding protein, adipocyte and Fatty acid-binding protein, epidermal Inhibitor 4-carbazol-9-yl-butyric Acid Family
No. of Seeds 3 No. of Other Members 11
Family Centroid CFAMM00244949 Functional Category Investigative Drug with Natural Product
Superfamily Setipiprant Superfamily
Class Class 1218

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Histamine H1 receptor Ligand (s)-(+)-dimethindene Maleate Family 6 12
Thromboxane A2 receptor Ligand Ramatroban Family 13 49
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
Growth hormone receptor Ligand EP-51216 Family 34 390
D(1B) dopamine receptor Ligand LE-300 Family 65 452
Histone deacetylase 1 Inhibitor Panobinostat Family 5 93
D(4) dopamine receptor Ligand SPI-376 Family 7 84
Setipiprant family 5 118
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 6 17
Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
Prostaglandin E synthase Inhibitor L-655240 Family 3 46
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
5-hydroxytryptamine receptor 2A Ligand 8-chloro-1,2,3,4-tetrah... 5 4
Cannabinoid receptor 2 Ligand JWH-204 Family 6 10
Cannabinoid receptor 2 Ligand JWH-249 Family 7 13
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 24 50
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 37 1
Trypsin Inhibitor 1-benzyl-1h-indole-5-carboxamidine Family 4 3
Fatty acid-binding protein, adipocyte Inhibitor 1-benzyl-2,3-d... 1 8
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Kinesin-like protein KIF11 Inhibitor 2-(trifluoromethyl)-9h-ca... 5 0
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 3 27
Aldose reductase Inhibitor 3-(3-benzoyl-1h-pyrrol-1-yl)propano... 3 7
Sodium-dependent serotonin transporter and Sodium-dependent do... 6 4
5-hydroxytryptamine receptor 2A and Alpha-1B adrenergic recept... 10 9
Prostaglandin D2 receptor 2 ligand SureCN2189431 family 7 1
Prostaglandin D2 receptor 2 ligand 2-[5-fluoro-2-methyl-3-[(4-... 3 5
Prostaglandin D2 receptor 2 and Prostaglandin G/H synthase 1 l... 3 17
Prostaglandin D2 receptor 2 ligand SureCN317401 family 3 8
Prostaglandin D2 receptor 2 and Cytochrome P450 2C19 ligand 2-... 6 13
Prostaglandin D2 receptor 2 ligand 2-[3-[(E)-2-cyano-3-(N-meth... 9 9
Thromboxane-A synthase inhibitor 5-Chloro-1-methyl-2-(3-pyridy... 1 0
Phospholipase A2, membrane associated inhibitor AGN-PC-075RBK ... 1 2
Nuclear receptor ROR-gamma and Prelamin-A/C ligand CHEMBL14461... 1 18
Cytochrome P450 2C19 inhibitor CHEMBL1449918 family 1 0
Indoles Metabolite Ethyl 3-methyl-9H-carbazole-9-carboxylate F... 1 1
NP (e)-9-(2-methoxy-2-(prop-1-en-1-yloxy)ethyl)-9h-carbazole F... 2 0
(2Z)-2-[(1,2-dimethylindol-3-yl)methylidene]-3-propan-2-yliden... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00244939 DNC005039 Investigative Drug 3-Carbazol-9-yl-propionic acid
CFAMM00244949 DNC005040 Investigative Drug 4-Carbazol-9-yl-butyric acid
CFAMM00244948 DNC005041 Investigative Drug 5-Carbazol-9-yl-pentanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26853 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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