CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1630
Family Name Sphingosine 1-phosphate receptor 1 Ligand [3-(4-nonyl-benzylamino)-propyl]-phosphonic Acid Family
No. of Seeds 9 No. of Other Members 22
Family Centroid CFAMM00245211 Functional Category Investigative Drug
Superfamily Sphingosine 1-phosphate receptor 1 Ligand [3-(4-nonyl-benzylamino)-propyl]-phosphonic Acid Superfamily
Class Class 1610

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor ligand phenethylamine derivative ... 12 283
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Noradrenergic re-uptake Inhibitor Phentermine Family 2 11
C-X-C chemokine receptor type 4 Ligand AMD-3100 Family 3 6
Glutamate receptor AMPA subtype and Noradrenaline uptake Ligan... 9 17
Adenosine receptor A3 and Glutamate receptor ionotropic, NMDA ... 4 30
Calcium-activated potassium channel subunit alpha-1 Ligand N-m... 2 10
Sodium-dependent serotonin transporter Inhibitor 1-(2-(naphtha... 5 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Aminopeptidase N Inhibitor (1-amino-2-phenyl-ethyl)-phosphinic... 3 11
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 1
Amine oxidase [flavin-containing] B Inhibitor Methyl-(1,2,3,4-... 2 0
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 3 6
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 17 9
Sodium-dependent serotonin transporter and Sodium-dependent no... 9 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 2
Prostatic acid phosphatase inhibitor Phosphonic acid, [1-napht... 1 0
Farnesyl pyrophosphate synthase inhibitor [1-hydroxy-3-[methyl... 4 1


External ID

Functional Category

Molecule Name

CFAMM00245236 CHEMBL119233 Bioactive AGN-PC-0750FU
CFAMM00245235 CHEMBL181597 Bioactive [(1S,3S)-3-[(4-nonylphenyl)methylamino]cyclohexyl]phosphonic acid
CFAMM00245233 CHEMBL119256 Bioactive SureCN14195630
CFAMM00245226 CHEMBL116981 Bioactive SureCN14195743
CFAMM00245219 CHEMBL432809 Bioactive SureCN14195646
CFAMM00245218 CHEMBL184879 Bioactive AGN-PC-075FFY
CFAMM00245231 CHEMBL325193 Bioactive AGN-PC-0750FV
CFAMM00245220 DNC007294 Investigative Drug 1-(4-nonylbenzyl)pyrrolidin-3-ylphosphonic acid
CFAMM00245211 DNC005071 Investigative Drug [3-(4-Nonyl-benzylamino)-propyl]-phosphonic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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