CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1632
Family Name Oestrogen receptor and Estrogen receptor beta Ligand 2-naphthalen-1-yl-benzooxazol-6-ol Family
No. of Seeds 4 No. of Other Members 51
Family Centroid CFAMM00245299 Functional Category Investigative Drug with Natural Product
Superfamily Substance-P receptor Ligand R 673 Superfamily
Class Class 994

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Benoxapr... 1 76
Substance-P receptor Ligand R 673 Family 2 127
FX005 family 2 1
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Fatty-acid amide hydrolase 1 Inhibitor (z)-1-(benzo[d]oxazol-2... 2 27
Oestrogen receptor and Estrogen receptor beta Ligand 2-(6-hydr... 9 22
Prostacyclin receptor and Prostaglandin E2 receptor EP3 subtyp... 4 17
Peroxisome proliferator-activated receptor alpha Ligand BMS-68... 10 16
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 1 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 3
Thyroid hormone receptor beta ligand CHEMBL1397256 family 1 12
Estrogen receptor beta and Estrogen receptor ligand (4Z)-4-(7-... 4 2
Estrogen receptor beta and Estrogen receptor ligand (2Z)-2-(2-... 1 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and Dual 3',5'... 27 20
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 14 24
Cysteinyl leukotriene receptor 1 ligand 4-oxo-7-[[3-(quinolin-... 4 17
Peroxisome proliferator-activated receptor gamma and Peroxisom... 7 2
Reverse transcriptase/RNaseH inhibitor 3-[2-(4,7-dichloro-1,3-... 1 5
Reverse transcriptase/RNaseH inhibitor 3-[2-(4,7-difluoro-1,3-... 3 1
Glucocorticoid receptor and Progesterone receptor ligand (8S,1... 2 0
Reverse transcriptase/RNaseH inhibitor 3-[2-(1-benzofuran-2-yl... 1 1
Arachidonate 5-lipoxygenase inhibitor (4E)-4-[(E,4Z)-4-(3H-1,3... 6 6
Reverse transcriptase/RNaseH inhibitor 3-(1,3-benzoxazol-2-ylm... 1 0
Integrase and Serine/threonine-protein kinase pim-1 inhibitor ... 3 0


External ID

Functional Category

Molecule Name

CFAMM00245254 CHEMBL183368 Bioactive (5Z)-5-(6-hydroxy-3H-1,3-benzoxazol-2-ylidene)-3-methylnaphthalen-1-one
CFAMM00245272 DNC005086 Investigative Drug 2-Adamantan-2-ylidenemethyl-benzooxazol-6-ol
CFAMM00245299 DNC005251 Investigative Drug 2-Naphthalen-1-yl-benzooxazol-6-ol
CFAMM00245288 DNC005249 Investigative Drug 2-(6-Hydroxy-naphthalen-1-yl)-benzooxazol-6-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



55287 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543