CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1633
Family Name Cathepsin K and Cathepsin S Inhibitor P2,p3 Ketoamide Derivative Family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00245326 Functional Category Investigative Drug
Superfamily Cathepsin K and Cathepsin S Binder Superfamily
Class Class 1127

Cousin Family NamesSeedsMembers
HIV-1 protease Inhibitor Atazanavir Family 16 58
Proteinase-activated receptor 1 Ligand SCH-530348 Family 20 215
FK506-binding protein 1A Inhibitor Gpi-1046 Family 4 10
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Integrin beta-3 Inhibitor Elarofiban Family 28 45
Delta-type opioid receptor Ligand H-poa-ser-gly-phe-leu-thr-oh... 5 12
Cathepsin K inhibitor 2,4-dimethylpentan-3-yl N-[(3S)-1-(isoqu... 1 0
Cathepsin K inhibitor SureCN14260267 family 4 0
Probable G-protein coupled receptor 142 ligand (2S)-2-[[(2R)-o... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00245328 CHEMBL362878 Bioactive SureCN14260221
CFAMM00245326 DNC005106 Investigative Drug P2,P3 Ketoamide derivative

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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