CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1635
Family Name Carbonic anhydrase 2 Inhibitor 3-nitro-benzenesulfonamide Family
No. of Seeds 3 No. of Other Members 19
Family Centroid CFAMM00245348 Functional Category Investigative Drug
Superfamily Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Superfamily
Class Class 379

Cousin Family NamesSeedsMembers
Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 9 88
Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Family 19 117
Mannose-6-phosphate isomerase Inhibitor Sulfanilamide Family 4 8
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-hydr... 3 3
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 3-chlo... 2 12
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-isot... 1 2
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-nitr... 1 3
Reverse transcriptase Inhibitor 1-nitro-2-(2-nitrophenylsulfon... 3 8
5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)pheny... 8 25
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor 3-((4-... 5 4
Prostaglandin G/H synthase 1 Inhibitor 4-amino-n-(2-chlorophen... 2 3
Gamma-aminobutyric acid receptor Ligand Toluene-1-diazonium-3-... 1 1
Carbonic anhydrase Inhibitor 4-amino-3-fluoro-5-iodobenzenesul... 1 0
Muscleblind-like protein 1 and Ferritin light chain inhibitor ... 1 1
Prothrombin and Trypsin-1 inhibitor 2-[(2-nitrophenyl)sulfonyl... 2 0


External ID

Functional Category

Molecule Name

CFAMM00245336 DNC005117 Investigative Drug 4-Nitro-benzenesulfonamide
CFAMM00245348 DNC005108 Investigative Drug 3-Nitro-benzenesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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