CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID164
Family Name D(2) dopamine receptor Ligand Ar-c68397aa Family
No. of Seeds 18 No. of Other Members 81
Family Centroid CFAMM00182770 Functional Category Investigative Drug
Superfamily D(2) dopamine receptor Ligand Ar-c68397aa Superfamily
Class Class 1442

Cousin Family NamesSeedsMembers
Beta-2 adrenergic receptor Ligand Formoterol Family 16 63
Beta-2 adrenergic receptor Ligand Procaterol Family 7 42
Beta-3 adrenergic receptor Ligand BMS-196085 Family 18 72
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 12 0
Beta-2 adrenergic receptor ligand N-[2-[[(2R)-2-hydroxy-2-(4-h... 5 0
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 1 0
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 12 1
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 12 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00182740 CHEMBL82663 Bioactive Sibenadet
CFAMM00182726 CHEMBL1221590 Bioactive SureCN3836158
CFAMM00182732 CHEMBL1221636 Bioactive 4-hydroxy-7-[(1R)-1-hydroxy-2-(4-phenylbutylamino)ethyl]-3H-1,3-benzothiazol-2-one
CFAMM00182712 CHEMBL1221589 Bioactive 4-hydroxy-7-[(1R)-1-hydroxy-2-(3-phenylpropylamino)ethyl]-3H-1,3-benzothiazol-2-one
CFAMM00182725 CHEMBL1807823 Bioactive 4-hydroxy-7-[(1R)-1-hydroxy-2-[2-[3-(2-phenylethylamino)propylsulfanyl]ethylamino]ethyl]-3H-1,3-benzothiazol-2-one
CFAMM00182679 CHEMBL1945292 Bioactive 4-hydroxy-7-[(1R)-1-hydroxy-2-[2-[3-[(2-methoxyethylamino)methyl]phenyl]ethylamino]ethyl]-3H-1,3-benzothiazol-2-one
CFAMM00182692 CHEMBL1221804 Bioactive 4-hydroxy-7-[(1R)-1-hydroxy-2-[3-(N-methylanilino)propylamino]ethyl]-3H-1,3-benzothiazol-2-one
CFAMM00182685 CHEMBL1807818 Bioactive 4-hydroxy-7-[(1R)-1-hydroxy-2-[3-[2-(2-phenylethoxy)ethylsulfanyl]propylamino]ethyl]-3H-1,3-benzothiazol-2-one
CFAMM00182698 CHEMBL1944695 Bioactive 4-hydroxy-7-[(1R)-1-hydroxy-2-[2-[4-[(2-phenylethylamino)methyl]phenyl]ethylamino]ethyl]-3H-1,3-benzothiazol-2-one
CFAMM00182724 CHEMBL1807821 Bioactive 4-hydroxy-7-[(1R)-1-hydroxy-2-[3-[2-(2-phenylethoxy)ethoxy]propylamino]ethyl]-3H-1,3-benzothiazol-2-one
CFAMM00182750 CHEMBL1807874 Bioactive 4-hydroxy-7-[(1R)-1-hydroxy-2-[3-[2-[methyl(2-phenylethyl)amino]ethoxy]propylamino]ethyl]-3H-1,3-benzothiazol-2-one
CFAMM00182704 CHEMBL1807817 Bioactive 4-hydroxy-7-[(1R)-1-hydroxy-2-[2-[3-(2-phenylethoxy)propylsulfanyl]ethylamino]ethyl]-3H-1,3-benzothiazol-2-one
CFAMM00182684 CHEMBL1807819 Bioactive 4-hydroxy-7-[(1R)-1-hydroxy-2-[3-[3-(2-phenylethoxy)propylsulfanyl]propylamino]ethyl]-3H-1,3-benzothiazol-2-one
CFAMM00182710 CHEMBL1221587 Bioactive 4-hydroxy-7-[(1R)-1-hydroxy-2-(2-phenylethylamino)ethyl]-3H-1,3-benzothiazol-2-one
CFAMM00182729 CHEMBL1945037 Bioactive 4-hydroxy-7-[(1R)-1-hydroxy-2-[2-[3-[(3-phenylpropylamino)methyl]phenyl]ethylamino]ethyl]-3H-1,3-benzothiazol-2-one
CFAMM00182755 CHEMBL1221541 Bioactive 7-[(1R)-2-[[(1R)-1-cyclohexylethyl]amino]-1-hydroxyethyl]-4-hydroxy-3H-1,3-benzothiazol-2-one
CFAMM00182770 DNC000253 Investigative Drug AR-C68397AA
CFAMM00182677 DNC012298 Investigative Drug 7-(2-Amino-ethyl)-4-hydroxy-3H-benzothiazol-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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