CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1645
Family Name Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-acetamido-5-sulfonamidoindane Family
No. of Seeds 6 No. of Other Members 2
Family Centroid CFAMM00245415 Functional Category Investigative Drug
Superfamily Carbonic anhydrase 1 and Carbonic anhydrase 2 Binder Superfamily 9
Class Class 109

Cousin Family NamesSeedsMembers
SUR1-type K(ATP) channel and SUR2-type K(ATP) channel Ligand T... 3 35
Thymidylate synthase Inhibitor N-[tosyl-d-prolinyl]amino-ethan... 1 10
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Carbonic anhydrase 2 Inhibitor 4-(2-aminoethyl)benzenesulfonam... 3 30
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-valp... 8 5
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-amin... 2 0
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
5-hydroxytryptamine receptor 6 ligand N-[[(1R)-6-(benzenesulfo... 8 2
Carbonic anhydrase 12 and Carbonic anhydrase 2 inhibitor AGN-P... 5 0
Bifunctional epoxide hydrolase 2 inhibitor N-cycloheptyl-1-(2,... 7 8
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 1 1
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-[car... 1 0


External ID

Functional Category

Molecule Name

CFAMM00245416 DNC005130 Investigative Drug N-(5-Sulfamoyl-indan-1-yl)-acetamide
CFAMM00245415 DNC005131 Investigative Drug 2-acetamido-5-sulfonamidoindane
CFAMM00245428 DNC006488 Investigative Drug 2-propylamido-5-sulfonamidoindane
CFAMM00245414 DNC009699 Investigative Drug 2-acetamido-2,3-dihydro-1H-indene-5-sulfonic acid
CFAMM00245423 DNC005162 Investigative Drug 2-Acetylamino-indan-5-sulfonic acid
CFAMM00245422 DNC006489 Investigative Drug 2-ethylamido-5-sulfonamidoindane

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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