CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1668
Family Name Oestrogen receptor and Estrogen receptor beta Ligand 2-(6-hydroxy-naphthalen-1-yl)-benzooxazol-5-ol Family
No. of Seeds 9 No. of Other Members 22
Family Centroid CFAMM00245805 Functional Category Investigative Drug
Superfamily Substance-P receptor Ligand R 673 Superfamily
Class Class 994

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Benoxapr... 1 76
Substance-P receptor Ligand R 673 Family 2 127
FX005 family 2 1
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Fatty-acid amide hydrolase 1 Inhibitor (z)-1-(benzo[d]oxazol-2... 2 27
Oestrogen receptor and Estrogen receptor beta Ligand 2-naphtha... 4 51
Prostacyclin receptor and Prostaglandin E2 receptor EP3 subtyp... 4 17
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-[4-(4-hydroxyphe... 1 4
Peroxisome proliferator-activated receptor alpha Ligand BMS-68... 10 16
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 1 4
Fatty-acid amide hydrolase 1 Inhibitor 3-(benzo[d]oxazol-2-yl)... 1 6
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 4 4
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 7
Peroxisome proliferator-activated receptor delta ligand SureCN... 8 19
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Thyroid hormone receptor beta ligand CHEMBL1397256 family 1 12
Estrogen receptor beta and Estrogen receptor ligand (4Z)-4-(7-... 4 2
Estrogen receptor beta and Estrogen receptor ligand (2Z)-2-(2-... 1 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 1
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 14 24
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 1
Peroxisome proliferator-activated receptor gamma and Peroxisom... 7 2
Reverse transcriptase/RNaseH inhibitor 3-[2-(4,7-dichloro-1,3-... 1 5
Reverse transcriptase/RNaseH inhibitor 3-[2-(4,7-difluoro-1,3-... 3 1
Glucocorticoid receptor and Progesterone receptor ligand (8S,1... 2 0
Cholesteryl ester transfer protein inhibitor AGN-PC-07R9U4 family 1 1
Reverse transcriptase/RNaseH inhibitor 3-[2-(1-benzofuran-2-yl... 1 1
Arachidonate 5-lipoxygenase inhibitor (4E)-4-[(E,4Z)-4-(3H-1,3... 6 6
Reverse transcriptase/RNaseH inhibitor 3-(1,3-benzoxazol-2-ylm... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00245792 CHEMBL486225 Bioactive (4Z)-2-fluoro-4-[7-[(E)-2-fluoroethenyl]-5-hydroxy-3H-1,3-benzoxazol-2-ylidene]cyclohexa-2,5-dien-1-one
CFAMM00245805 DNC005252 Investigative Drug 2-(6-Hydroxy-naphthalen-1-yl)-benzooxazol-5-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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