CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1669
Family Name Acetylcholinesterase Inhibitor 3-[2-(1-benzyl-piperidin-4-yl)-ethyl]-1h-indazole Family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00245814 Functional Category Investigative Drug
Superfamily Cytochrome P450 3A4 and Acetylcholinesterase Binder Superfamily
Class Class 826

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 12 108
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(1B) dopamine receptor Ligand LE-300 Family 65 452
NKP-1339 family 3 7
Prothrombin Inhibitor 4-[3-(4-chlorophenyl)-1h-pyrazol-5-yl]pi... 7 39
Tyrosine-protein kinase JAK2 Inhibitor 5-phenyl-1h-indazol-3-a... 1 7
D(2) dopamine receptor and D(3) dopamine receptor Ligand 1-(4-... 10 48
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 6
Glucocorticoid receptor and Oxysterols receptor LXR-alpha Liga... 4 13
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand N-(1h... 2 12
Kappa-type opioid receptor and Potassium voltage-gated channel... 10 10
Cytochrome P450 3A4 Inhibitor 5-(2-phenethylpiperazin-1-yl)-1h... 12 35
5-hydroxytryptamine receptor 6 Ligand 4-(piperazin-1-yl)-3-tos... 18 75
Tyrosine-protein kinase ITK/TSK inhibitor (3Z)-3-(6-methylindo... 2 40
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 4 3
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 3 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0
Aurora kinase B and Aurora kinase A inhibitor SureCN5594082 fa... 2 3
Microtubule-associated protein tau inhibitor CHEMBL1544706 family 1 0
Serine/threonine-protein kinase Chk1 inhibitor N-[[3-(4-fluoro... 1 4


External ID

Functional Category

Molecule Name

CFAMM00245814 DNC005254 Investigative Drug 3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-1H-indazole
CFAMM00245818 DNC005850 Investigative Drug Phenyl-(3-phenyl-1H-indazol-6-yl)-amine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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