CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1694
Family Name Kappa-type opioid receptor Ligand Salvinorin B Butoxymethyl Ether Family
No. of Seeds 38 No. of Other Members 215
Family Centroid CFAMM00247049 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Kappa-type opioid receptor Binder Superfamily
Class Class 987

Cousin Family NamesSeedsMembers
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 10
Arachidonate 15-lipoxygenase Inhibitor Igernellin Family 2 30
Kappa-type opioid receptor Ligand 2-epi-2-thiosalvinorin B Family 6 7
Phospholipase A2 Inhibitor Helenaquinone Family 2 5
Creatine kinase Inhibitor 5-(4'-benzoylbiphenyl-4-yl)-2-furoic... 2 66
Survival motor neuron protein and Retinal dehydrogenase 1 inhi... 1 11
Kappa-type opioid receptor ligand methyl (2S,4aR,6aR,7R,9S,10a... 5 19
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 78
Multidrug resistance protein 1 inhibitor CHEMBL1829397 family 5 8
Multidrug resistance protein 1 inhibitor CHEMBL394284 family 5 4
Naphthofurans Metabolite (3beta,6beta)-Furanoeremophilane-3,6-... 1 0
Prenol Lipids Metabolite Ipomeamaronol Family 2 2
NP 6-(4-ethoxyphenyl)-1,3-dimethyl-4-oxo-4h-cyclohepta[c]furan... 13 3
1,3-dimethylcyclohepta[c]furan-8-one NP 8-hydroxy-6-(4-methoxy... 10 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00246639 CHEMBL371079 Bioactive methyl (2S,6aR,7R,9S,10bR)-9-carbamoyloxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
CFAMM00246702 CHEMBL196789 Bioactive methyl (2S,6aR,7R,9S,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-9-propanoyloxy-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
CFAMM00246856 CHEMBL257922 Bioactive methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(1-ethoxyethoxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
CFAMM00246778 CHEMBL178960 Bioactive SureCN13008278
CFAMM00246989 CHEMBL370272 Bioactive divinorin propionate
CFAMM00247000 CHEMBL180126 Bioactive methyl (2S,4aR,6aR,7R,9S,10bR)-2-(furan-3-yl)-9-(methoxymethoxy)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
CFAMM00246501 CHEMBL2381584 Bioactive 3-O-[(2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-7-methoxycarbonyl-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromen-9-yl] 1-O-methyl propanedioate
CFAMM00246708 CHEMBL370678 Bioactive methyl (2S,4aR,6aR,7R,9S,10aR,10bS)-9-acetyloxy-2-(furan-3-yl)-6a,10b-dimethyl-10-oxo-1,2,4,4a,5,6,7,8,9,10a-decahydrobenzo[f]isochromene-7-carboxylate
CFAMM00246883 CHEMBL193735 Bioactive SureCN13008513
CFAMM00246744 CHEMBL1941031 Bioactive methyl (2R,4aR,6aR,7R,9S,10aS,10bR)-9-(ethoxymethoxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
CFAMM00246782 CHEMBL458234 Bioactive SureCN10071902
CFAMM00246957 CHEMBL194545 Bioactive methyl (2S,6aR,7R,9S,10aS,10bR)-9-acetyloxy-2-(furan-3-yl)-6a,10b-dimethyl-10-oxo-1,2,5,6,7,8,9,10a-octahydrobenzo[f]isochromene-7-carboxylate
CFAMM00246981 CHEMBL193787 Bioactive methyl (2S,6aR,7R,9S,10bR)-9-ethoxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
CFAMM00246820 CHEMBL379138 Bioactive methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-butanoyloxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
CFAMM00246647 CHEMBL445332 Bioactive Salvinorin A
CFAMM00246581 CHEMBL378767 Bioactive methyl (2S,4aR,6aR,7R,9R,10aS,10bR)-9-acetyloxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
CFAMM00246743 CHEMBL1941030 Bioactive methyl (2R,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethoxy)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
CFAMM00246780 CHEMBL196099 Bioactive methyl (2S,6aR,7R,9S,10bR)-9-butanoyloxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
CFAMM00247049 DNC008130 Investigative Drug salvinorin B butoxymethyl ether
CFAMM00246460 DNC005337 Investigative Drug SALVINORIN A
CFAMM00246416 DNC008142 Investigative Drug salvinorin B ethoxymethyl ether
CFAMM00246504 DNC009387 Investigative Drug 12-EPI-SALVINORIN A
CFAMM00247048 DNC008137 Investigative Drug salvinorin B 2,2,2-trifluoroethoxymethyl ether
CFAMM00246459 DNC005338 Investigative Drug HERKINORIN
CFAMM00246415 DNC008143 Investigative Drug salvinorin B methoxymethyl ether
CFAMM00246787 DNC006845 Investigative Drug DEOXY SALVINORIN A
CFAMM00247047 DNC008136 Investigative Drug salvinorin B 2-methoxyethoxymethyl ether
CFAMM00246414 DNC008140 Investigative Drug salvinorin B isopropoxymethyl ether
CFAMM00246785 DNC006846 Investigative Drug SALVINORIN B
CFAMM00247046 DNC008135 Investigative Drug salvinorin B benzyloxymethyl ether
CFAMM00246413 DNC008141 Investigative Drug salvinorin B propoxymethyl ether
CFAMM00246852 DNC008128 Investigative Drug salvinorin B 2-methoxy-2-propyl ether
CFAMM00247045 DNC008134 Investigative Drug salvinorin B methylthiomethyl ether
CFAMM00247052 DNC008133 Investigative Drug salvinorin B fluoromethyl ether
CFAMM00247042 DNC008139 Investigative Drug salvinorin B tert-butoxymethyl ether
CFAMM00246851 DNC008129 Investigative Drug salvinorin B tetrahydropyran-2-yl ether
CFAMM00247050 DNC008131 Investigative Drug salvinorin B 1-ethoxyethyl ether
CFAMM00247041 DNC008138 Investigative Drug salvinorin B 2-fluoroethoxymethyl ether

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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