CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1696
Family Name Gonadotropin-releasing hormone receptor Ligand Azaline B Family
No. of Seeds 12 No. of Other Members 0
Family Centroid CFAMM00247140 Functional Category Investigative Drug
Superfamily Gonadotropin-releasing hormone Inhibitor ASP3550 Superfamily
Class Class 980

Cousin Family NamesSeedsMembers
Gonadotropin-releasing hormone receptor Ligand decapeptide ana... 9 162
Gastrin/cholecystokinin type B receptor ligand peptide Pentaga... 26 1171
Somatostatin receptor type 2 ligand octapeptide Octreotide Family 27 172
Growth hormone receptor Ligand EP-51216 Family 34 390
ABC294640 family 5 75
Gonadotropin-releasing hormone Inhibitor ASP3550 Family 33 60
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[n... 12 10
Gonadotropin-releasing hormone receptor Ligand [d-ncy(methyl)4... 32 0
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Endothelin B receptor Ligand IRL-2500 Family 34 87
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Coagulation factor X and Prothrombin inhibitor SureCN8243313 f... 10 8
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 1
Gonadotropin-releasing hormone receptor ligand (3S)-3-[[(2S)-2... 5 0
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00247142 CHEMBL415549 Bioactive CHEMBL415549
CFAMM00247134 CHEMBL2370818 Bioactive (2R)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-6-[(5-amino-1H-1,2,4-triazol-3-yl)amino]hexanoyl]amino]-6-[(5-amino-1H-1,2,4-triazol-3-yl)amino]hexanoyl]amino]-4-methylpentanoyl]amino]-6-(propan-2-ylamino)hexanoyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
CFAMM00247141 CHEMBL415547 Bioactive CHEMBL415547
CFAMM00247133 CHEMBL2370814 Bioactive (2R)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-6-[(5-amino-1H-1,2,4-triazol-3-yl)amino]hexanoyl]amino]-6-[(5-amino-1H-1,2,4-triazol-3-yl)amino]hexanoyl]amino]-4-methylpentanoyl]amino]-6-(propan-2-ylamino)hexanoyl]-N-[2-(ethylamino)-2-oxoethyl]pyrrolidine-2-carboxamide
CFAMM00247139 CHEMBL268146 Bioactive CHEMBL268146
CFAMM00247146 CHEMBL414514 Bioactive CHEMBL414514
CFAMM00247138 CHEMBL2370807 Bioactive (2R)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-5-[(5-amino-1H-1,2,4-triazol-3-yl)amino]pentanoyl]amino]-5-[(5-amino-1H-1,2,4-triazol-3-yl)amino]pentanoyl]amino]-4-methylpentanoyl]amino]-6-(propan-2-ylamino)hexanoyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
CFAMM00247144 CHEMBL402671 Bioactive CHEMBL402671
CFAMM00247137 CHEMBL2370803 Bioactive (2R)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-6-[(5-amino-1H-1,2,4-triazol-3-yl)amino]hexanoyl]amino]-6-[(5-amino-1H-1,2,4-triazol-3-yl)amino]hexanoyl]amino]-4-methylpentanoyl]amino]-6-(propan-2-ylamino)hexanoyl]-N-(2-amino-2-oxoethyl)pyrrolidine-2-carboxamide
CFAMM00247143 CHEMBL268875 Bioactive CHEMBL268875
CFAMM00247136 CHEMBL414469 Bioactive CHEMBL414469
CFAMM00247140 DNC005340 Investigative Drug AZALINE B

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26834 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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