CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1697
Family Name NF-kappa-B Inhibitor Miller-9z-enolide Family
No. of Seeds 10 No. of Other Members 147
Family Centroid CFAMM00247352 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily NF-kappa-B and Nuclear factor NF-kappa-B p100 subunit Binder Superfamily
Class Class 2209

Cousin Family NamesSeedsMembers
Arglabin family 4 38
Fatty acid synthase and Carnitine O-palmitoyltransferase 1, mu... 1 1
NF-kappa-B Inhibitor 2-oxoguaia-1,4,11(13)-trien-12,8alpha-oli... 4 18
NF-kappa-B and Nuclear factor NF-kappa-B p100 subunit Inhibito... 2 2
NF-kappa-B and Nuclear factor NF-kappa-B p100 subunit Inhibito... 7 1
NF-kappa-B Inhibitor Helenalinmethacrylate Family 3 17
UDP-N-acetylglucosamine 1-carboxyvinyltransferase Inhibitor Eu... 3 1
NF-kappa-B Inhibitor 2beta-methoxy-2-deethoxyphantomolin Family 1 2
Sarcoplasmic/endoplasmic reticulum calcium ATPase Inhibitor Th... 7 13
Protein kinase C alpha type inhibitor NSC703748 family 18 12
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial ... 21 26
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial ... 5 0
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial ... 2 1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial ... 5 1
Protein kinase C alpha type inhibitor [(4E)-2-(hydroxymethyl)-... 16 2
Protein kinase C delta type and Protein kinase C alpha type in... 1 0
Protein kinase C alpha type inhibitor [(4Z)-2-hydroxy-4-[5-met... 1 0
Protein kinase C alpha type inhibitor [2-(hydroxymethyl)-5-oxo... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00247360 CHEMBL383708 Bioactive [(4E)-2-(hydroxymethyl)-4-[5-methyl-3-(2-methylpropyl)hexylidene]-5-oxooxolan-2-yl]methyl octanoate
CFAMM00247391 CHEMBL206332 Bioactive [(4Z)-2-(hydroxymethyl)-4-[5-methyl-3-(2-methylpropyl)hexylidene]-5-oxooxolan-2-yl]methyl octanoate
CFAMM00247351 DNC006375 Investigative Drug 1beta-methoxy-miller-9Z-enolide
CFAMM00247350 DNC006374 Investigative Drug 4beta,15-epoxy-miller-9E-enolide
CFAMM00247355 DNC006373 Investigative Drug 4beta,15-epoxy-miller-9Z-enolide
CFAMM00247384 DNC005376 Investigative Drug MOLEPHANTININ
CFAMM00247354 DNC006372 Investigative Drug 9alpha-acetoxy-miller-1(10)Z-enolide
CFAMM00247353 DNC006377 Investigative Drug miller-9E-enolide
CFAMM00247381 DNC005375 Investigative Drug MOLEPHANTIN
CFAMM00247352 DNC006376 Investigative Drug miller-9Z-enolide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27635 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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