CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1706
Family Name C-X-C chemokine receptor type 1 and C-X-C chemokine receptor type 2 Ligand 2-[3-(1-hydroxy-propyl)-phenyl]-propionic Acid Family
No. of Seeds 2 No. of Other Members 53
Family Centroid CFAMM00247592 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily C-X-C chemokine receptor type 1 and C-X-C chemokine receptor type 2 Ligand 2-[3-(1-hydroxy-propyl)-phenyl]-propionic Acid Superfamily
Class Class 907

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor ligand opiate Meperidine Family 13 76
Retinoid X receptor Ligand Bexarotene Family 7 492
Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
Prostaglandin G/H synthase 2 Inhibitor Ketoprofen Family 5 84
Benzyl Alcohol family 1 73
CPI-613 family 4 35
Carbonic anhydrase 2 Inhibitor 4-(hydroxymercury)benzoic Acid ... 7 97
Renin Inhibitor 3-phenyl-1,2-propandiol Family 2 43
Nicotinate-nucleotide pyrophosphorylase [carboxylating] Inhibi... 2 119
Carboxypeptidase B2 Inhibitor Dl-benzylsuccinic Acid Family 1 11
Liver carboxylesterase 1 Inhibitor 1,2-bis(2,5-difluorophenyl)... 12 10
Glutamate carboxypeptidase 2 Inhibitor 2-(3-carboxybenzyl)succ... 2 7
Glutamate carboxypeptidase 2 Inhibitor 2-(3-cyanobenzyl)-5-mer... 1 0
Glutamate carboxypeptidase 2 Inhibitor 3-(2-carboxy-6-mercapto... 9 4
Calcium-activated potassium channel subunit alpha-1 Ligand Tri... 1 10
Protein kinase C delta type and Protein kinase C alpha type In... 4 105
Collagenase 3 and Macrophage metalloelastase Inhibitor 5-(4'-c... 4 43
Solute carrier family 52, riboflavin transporter, member 2 Inh... 1 7
Fatty-acid amide hydrolase 1 Inhibitor 3-(ethoxycarbonyl)pheny... 2 69
Trypsin-1 and Prothrombin inhibitor (3S,3aR,6aS)-3-benzyl-3,3a... 2 23
Arachidonate 15-lipoxygenase inhibitor SureCN9469035 family 6 40
UDP-glucuronosyltransferase 2B7 and UDP-glucuronosyltransferas... 1 5
Prostaglandin E2 receptor EP2 subtype ligand 4-[2-[(1R,3R)-3-h... 1 6
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 18
Beta-lactamase inhibitor CHEMBL1358094 family 1 10
Hydroxycarboxylic acid receptor 2 and Hydroxycarboxylic acid r... 3 0
Thromboxane A2 receptor ligand (Z)-7-[(4S,5R)-2,2-dimethyl-4-p... 2 9
Angiotensin-converting enzyme inhibitor AGN-PC-00NKX7 family 2 2
Benzyloxycarbonyls Metabolite Benzyl acetate Family 5 53
Indanes Metabolite (R)-Pterosin B Family 5 8
Indanes Metabolite (10S,11S)-Pterosin C Family 2 2
Benzyl Alcohols and Derivatives Metabolite (2R,3S)-Piscidic ac... 1 1
Carboxylic Acids and Derivatives Metabolite 3-Acetoxy-3-methyl... 2 0
Benzyloxycarbonyls Metabolite Benzyl acetoacetate Family 1 6
[(1S,2S,5R)-2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclohexyl] ben... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00247592 DNC005401 Investigative Drug 2-[3-(1-Hydroxy-propyl)-phenyl]-propionic acid
CFAMM00247617 DNC012738 Investigative Drug 4-Hydroxy-4-phenyl-butyric acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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