CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1715
Family Name Liver carboxylesterase 1 Inhibitor 2,2-dimethoxy-1,2-diphenyl-ethanone Family
No. of Seeds 1 No. of Other Members 16
Family Centroid CFAMM00248098 Functional Category Investigative Drug with Natural Product
Superfamily Presenilin-1 and Liver carboxylesterase 1 Binder Superfamily
Class Class 2216

Cousin Family NamesSeedsMembers
Retinoid X receptor Ligand Bexarotene Family 7 492
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
DNA topoisomerase 1 Inhibitor Beta-lapachone Family 3 66
Carbonic anhydrase 2 Inhibitor 4-(hydroxymercury)benzoic Acid ... 7 97
Nicotinate-nucleotide pyrophosphorylase [carboxylating] Inhibi... 2 119
Steryl-sulfatase Inhibitor Sulfamic Acid 4-(3-methoxy-benzoyl)... 5 24
Liver carboxylesterase 1 Inhibitor 1,2-bis(2,5-difluorophenyl)... 12 10
Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor (5r,... 3 9
Thyroid hormone receptor beta Ligand (4-hexylphenyl)(oxiran-2-... 1 16
Protein kinase C delta type and Protein kinase C alpha type In... 4 105
Fatty-acid amide hydrolase 1 Inhibitor 3-(ethoxycarbonyl)pheny... 2 69
Cellular tumor antigen p53 and Thyrotropin receptor ligand CHE... 1 19
RAC-alpha serine/threonine-protein kinase inhibitor CHEMBL4754... 2 17
Arachidonate 15-lipoxygenase inhibitor SureCN9469035 family 6 40
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 10
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 18
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Benzyloxycarbonyls Metabolite Benzyl acetate Family 5 53
Epoxides Metabolite Phenylmethylglycidic ester Family 2 17
Aromatic Homomonocyclic Compounds Metabolite Dimethylbenzyl ca... 2 11
[(1S,2S,5R)-2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclohexyl] ben... 1 2
3-methyl-1-oxo-4H-isochromene-3-carboxylate NP Methyl 3-methyl... 4 1
4-hydroxy-2-(4-methoxycarbonylphenyl)-4-methyl-6-oxocyclohexan... 15 2
carboxylate NP ZINC04026424 Family 3 7
(4,5-dioxooxolan-3-ylidene)-phenylmethanolate NP Agn-pc-03fjc2... 1 0
methylbenzoate NP 7-oxocyclohepta-1,3,5-trien-1-yl 3-methylben... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00248098 DNC005433 Investigative Drug 2,2-Dimethoxy-1,2-diphenyl-ethanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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