CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1724
Family Name Liver carboxylesterase 1 Inhibitor 1-(4-chloro-phenyl)-2-phenyl-ethane-1,2-dione Family
No. of Seeds 5 No. of Other Members 47
Family Centroid CFAMM00248423 Functional Category Investigative Drug
Superfamily Liver carboxylesterase 1 Inhibitor 1-(4-chloro-phenyl)-2-phenyl-ethane-1,2-dione Superfamily
Class Class 2221

Cousin Family NamesSeedsMembers
Aldehyde oxidase inhibitor para-naphthoquinone Menadione Family 22 503
Vitamin K epoxide reductase complex subunit 1 Inhibitor Phenin... 5 44
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Diet... 29 276
Cathepsin L1 Inhibitor Biphenyl-4-yl-acetaldehyde Family 2 86
Cytosolic phospholipase A2 Inhibitor 1,1,1,2,2-pentafluoro-8-p... 11 18
Liver carboxylesterase 1 Inhibitor 1,2-bis(2,3,6-trifluorophen... 16 11
Liver carboxylesterase 1 Inhibitor 1,2-bis-(4-bromo-phenyl)-et... 2 26
72 kDa type IV collagenase and Macrophage metalloelastase Inhi... 2 5
Glutathione reductase, mitochondrial and Trypanothione reducta... 2 5
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 2 8
Liver carboxylesterase 1 Inhibitor Acenanthrene-9,10-dione Family 2 12
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1-phe... 6 23
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1-(3,... 2 5
Arachidonate 5-lipoxygenase Inhibitor 1,8-dichloro-10h-anthrac... 1 6
4-hydroxyphenylpyruvate dioxygenase Inhibitor 2-(2-iodo-benzoy... 3 1
Prostaglandin G/H synthase 1 Inhibitor 5-(4-chlorophenyl)-4-p-... 2 0
Neuraminidase Inhibitor (e,e)-1,7-diphenyl-4,6-heptadien-3-one... 2 5
Sigma non-opioid intracellular receptor 1 ligand N-Phprop-clph... 1 12
Melanin-concentrating hormone receptor 1 ligand 1-(3-acetyl-1,... 8 4
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 0
Progesterone receptor ligand AGN-PC-07COX3 family 1 4
Gamma-aminobutyric acid receptor subunit alpha-5 and Gamma-ami... 2 0
2-[(2,4-dichlorophenyl)methylidene]-4,4,6,6-tetramethylbicyclo... 6 1


External ID

Functional Category

Molecule Name

CFAMM00248423 DNC005465 Investigative Drug 1-(4-Chloro-phenyl)-2-phenyl-ethane-1,2-dione
CFAMM00248400 DNC011738 Investigative Drug 2-(2-Chloro-benzoyl)-cyclohexane-1,3-dione
CFAMM00248385 DNC005453 Investigative Drug 1,2-Bis-(2-chloro-phenyl)-ethane-1,2-dione
CFAMM00248384 DNC005452 Investigative Drug 1,2-Bis-(4-chloro-phenyl)-ethane-1,2-dione
CFAMM00248425 DNC005466 Investigative Drug 1-(4-Chloro-phenyl)-2-p-tolyl-ethane-1,2-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



72051 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543