CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1727
Family Name Liver carboxylesterase 1 Inhibitor 1-(4-nitro-phenyl)-2-phenyl-ethane-1,2-dione Family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00248471 Functional Category Investigative Drug
Superfamily Cholinesterase and Acetylcholinesterase Binder Superfamily 2
Class Class 2224

Cousin Family NamesSeedsMembers
4-hydroxyphenylpyruvate dioxygenase Inhibitor Nitisinone Family 4 43
Poly [ADP-ribose] polymerase 1 Inhibitor BSI-201 Family 3 16
Pan-DAC Inhibitor AR-42 Family 21 153
Urokinase-type plasminogen activator Inhibitor 1-[4-(2-oxo-2-p... 1 3
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 13
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 1 9
Telomerase reverse transcriptase Inhibitor 2,7-dinitroantraqui... 3 8
Acetylcholinesterase and Cholinesterase Inhibitor 5,6-dinitroa... 1 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1-(4-... 1 9
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 2 17
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 7
D(4) dopamine receptor ligand AGN-PC-074VC9 family 2 3
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 0
Aromatase inhibitor AGN-PC-00Q2PJ family 4 0
D-alanyl-D-alanine carboxypeptidase and Penicillin-binding pro... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00248471 DNC005478 Investigative Drug 1-(4-Nitro-phenyl)-2-phenyl-ethane-1,2-dione
CFAMM00248467 DNC011691 Investigative Drug 2'-Nitro-biphenyl-4-carboxylic acid hydroxyamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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