CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1730
Family Name Aldose reductase Inhibitor Lidorestat Family
No. of Seeds 16 No. of Other Members 27
Family Centroid CFAMM00248604 Functional Category Investigative Drug
Superfamily Aldose reductase Inhibitor Lidorestat Superfamily
Class Class 2226

Cousin Family NamesSeedsMembers
Prostaglandin D2 receptor 2 Ligand AZD1981 Family 11 28
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 20
Prostaglandin D2 receptor 2 and Aldose reductase ligand 2-[5-c... 1 0
Prostaglandin D2 receptor 2 ligand 2-[3-(4-chlorophenyl)sulfan... 2 1
Amyloid beta A4 protein and Luciferin 4-monooxygenase inhibito... 11 46
D(4) dopamine receptor ligand SureCN8706945 family 4 10
Aldose reductase inhibitor SureCN8658174 family 3 9


External ID

Functional Category

Molecule Name

CFAMM00248627 CHEMBL192886 Bioactive SureCN445966
CFAMM00248620 CHEMBL189801 Bioactive SureCN443785
CFAMM00248626 CHEMBL231690 Bioactive 2-[5-[[4-methyl-2-(trifluoromethyl)-1,3-thiazol-5-yl]methylsulfanyl]indol-1-yl]acetic acid
CFAMM00248625 CHEMBL371991 Bioactive SureCN443930
CFAMM00248618 CHEMBL192927 Bioactive SureCN443358
CFAMM00248631 CHEMBL2181805 Bioactive 2-[3-(1,3-benzothiazol-2-ylmethyl)-5-fluoro-2-methylindol-1-yl]acetic acid
CFAMM00248610 CHEMBL192263 Bioactive SureCN420980
CFAMM00248624 CHEMBL192167 Bioactive SureCN444349
CFAMM00248630 CHEMBL370478 Bioactive SureCN421166
CFAMM00248596 CHEMBL363387 Bioactive Lidorestat
CFAMM00248609 CHEMBL191508 Bioactive SureCN420815
CFAMM00248616 CHEMBL371162 Bioactive SureCN445827
CFAMM00248629 CHEMBL193569 Bioactive SureCN421176
CFAMM00248595 CHEMBL364235 Bioactive SureCN421162
CFAMM00248621 CHEMBL193155 Bioactive AGN-PC-007BS0
CFAMM00248604 DNC005485 Investigative Drug LIDORESTAT

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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