CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1731
Family Name Presenilin-1 and Presenilin-2 Inhibitor 1-chloro-4-(1-phenyl-cyclohexanesulfonyl)-benzene Family
No. of Seeds 5 No. of Other Members 13
Family Centroid CFAMM00248636 Functional Category Investigative Drug
Superfamily Presenilin-1 and Presenilin-2 Inhibitor 1-chloro-4-(1-phenyl-cyclohexanesulfonyl)-benzene Superfamily
Class Class 2227

Cousin Family NamesSeedsMembers
Gamma secretase Inhibitor MK-0752 Family 4 15
Cytochrome P450 11B1, mitochondrial Inhibitor 3-meso2-dde Family 2 14
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 11 80
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand SCH-3... 17 21
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 4 4
Prostaglandin G/H synthase 2 inhibitor SureCN8385166 family 4 2
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 0
Prostaglandin G/H synthase 2 inhibitor AGN-PC-075FEE family 4 2
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 7 0
Presenilin-1 and Presenilin-2 inhibitor AGN-PC-050UV0 family 3 0
Presenilin-1 and Presenilin-2 inhibitor AGN-PC-03IE0Y family 3 0
Presenilin-1 and Presenilin-2 inhibitor AGN-PC-050UV5 family 1 0
Presenilin-1 and Presenilin-2 inhibitor SureCN14085741 family 12 1
Presenilin-1 and Presenilin-2 inhibitor 3-[(1S,3S)-3-(4-chloro... 2 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 2
Presenilin-1 and Presenilin-2 inhibitor AGN-PC-00BXZ4 family 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00248635 CHEMBL200790 Bioactive AGN-PC-03IDZH
CFAMM00248645 CHEMBL200864 Bioactive AGN-PC-03IDYJ
CFAMM00248644 CHEMBL425566 Bioactive SureCN4813463
CFAMM00248639 CHEMBL380819 Bioactive AGN-PC-03IE0A
CFAMM00248636 DNC005486 Investigative Drug 1-Chloro-4-(1-phenyl-cyclohexanesulfonyl)-benzene

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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