CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1744
Family Name Oestrogen receptor and Estrogen receptor beta Ligand 1-bromo-6-(4-hydroxy-phenyl)-naphthalen-2-ol Family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00249096 Functional Category Investigative Drug
Superfamily Oestrogen receptor and Estrogen receptor beta Ligand 1-bromo-6-(4-hydroxy-phenyl)-naphthalen-2-ol Superfamily
Class Class 2232

Cousin Family NamesSeedsMembers
Oestrogen receptor ligand steroid Estradiol Family 18 147
Oestrogen receptor ligand Dienestrol Family 35 440
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
Estrogen receptor beta Ligand 1-chloro-6-(4-hydroxyphenyl)-2-n... 12 23
Oestrogen receptor and Estrogen receptor beta Ligand 6-(4-hydr... 30 63
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
Indoleamine 2,3-dioxygenase 1 Inhibitor Naphthalene-1,4-diol F... 2 4
Tyrosinase Inhibitor 4-(6-hydroxynaphthalen-2-yl)benzene-1,3-d... 4 2
Estrogen receptor beta and Estrogen receptor ligand (4Z)-2-flu... 2 0
Androgen receptor and Progesterone receptor ligand diarylpheno... 1 1


External ID

Functional Category

Molecule Name

CFAMM00249095 CHEMBL195039 Bioactive AGN-PC-005NED
CFAMM00249092 DNC009537 Investigative Drug 1-Bromo-6-(3-hydroxyphenyl)-2-naphthol
CFAMM00249096 DNC005600 Investigative Drug 1-Bromo-6-(4-hydroxy-phenyl)-naphthalen-2-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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