CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 5-hydroxytryptamine receptor Ligand Bay X3702 Family
No. of Seeds 3 No. of Other Members 12
Family Centroid CFAMM00183073 Functional Category Investigative Drug
Superfamily ATP-sensitive inward rectifier potassium channel 10 Ligand Gliquidone Superfamily
Class Class 511

Cousin Family NamesSeedsMembers
G protein-activated inward rectifier potassium channel 4 ligan... 6 9
D(2) dopamine receptor Ligand Sulpiride Family 7 38
ATP-sensitive inward rectifier potassium channel 10 Ligand Gli... 1 2
5-hydroxytryptamine receptor 1A Ligand Robalzotan Family 9 41
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 7 12
Pol polyprotein inhibitor AC1LA9K7 family 7 23
Survival motor neuron protein and Retinal dehydrogenase 1 inhi... 2 9
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Kappa-type opioid receptor and Delta-type opioid receptor liga... 3 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0
Carbonic anhydrase 2 and Carbonic anhydrase 9 inhibitor zinc;4... 4 0


External ID

Functional Category

Molecule Name

CFAMM00183079 CHEMBL51561 Bioactive AGN-PC-04S9PP
CFAMM00183068 CHEMBL1926761 Bioactive 2-[4-(3,4-dihydro-2H-chromen-2-ylmethylamino)butyl]-1,1-dioxo-1,2-benzothiazol-3-one
CFAMM00183073 DNC000279 Investigative Drug Bay x3702

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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