CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1752
Family Name Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 11B1, mitochondrial Inhibitor 5-[5-fluoro-indan-(1e)-ylidenemethyl]-pyrimidine Family
No. of Seeds 4 No. of Other Members 30
Family Centroid CFAMM00249371 Functional Category Investigative Drug
Superfamily Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 11B1, mitochondrial Inhibitor 5-[5-fluoro-indan-(1e)-ylidenemethyl]-pyrimidine Superfamily
Class Class 2236

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... 14 498
Peptide deformylase, mitochondrial Inhibitor Pyrimethamine Family 10 145
Reverse transcriptase Inhibitor Dapivirine Family 5 72
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Metabotropic glutamate receptor 5 Ligand 2-m-tolyl-1,8-naphthy... 7 11
Cathepsin K Inhibitor 4-phenyl-6-propylpyrimidine-2-carbonitri... 6 10
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-amin... 4 11
Macrophage migration inhibitory factor Inhibitor 4-iodo-6-phen... 5 4
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
Metabotropic glutamate receptor 5 Ligand 5-(2-m-tolylethynyl)p... 7 49
Metabotropic glutamate receptor 5 Ligand 5-(2-(3-chlorophenyl)... 2 13
Acetylcholinesterase Inhibitor N-benzyl-2-morpholinopyrimidin-... 6 16
Cathepsin K and Cathepsin L1 inhibitor 5-[3-(3,4-dihydro-1H-is... 2 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 6 10
Dihydropyrimidine dehydrogenase [NADP(+)] inhibitor 5-[(E)-2-p... 1 0
Sigma non-opioid intracellular receptor 1 and Alpha-1B adrener... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00249370 DNC005628 Investigative Drug 5-[5-Fluoro-indan-(1Z)-ylidenemethyl]-pyrimidine
CFAMM00249402 DNC013909 Investigative Drug 5-(2-(3,5-difluorophenyl)ethynyl)pyrimidine
CFAMM00249379 DNC013718 Investigative Drug 5-(phenylethynyl)pyrimidine
CFAMM00249371 DNC005627 Investigative Drug 5-[5-Fluoro-indan-(1E)-ylidenemethyl]-pyrimidine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27425 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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