CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1762
Family Name Poly [ADP-ribose] polymerase 1 Inhibitor KU-58684 Family
No. of Seeds 6 No. of Other Members 40
Family Centroid CFAMM00249655 Functional Category Investigative Drug with Natural Product
Superfamily Poly [ADP-ribose] polymerase 1 Inhibitor KU-58684 Superfamily
Class Class 2241

Cousin Family NamesSeedsMembers
Troponin C, slow skeletal and cardiac muscles Inhibitor Levosi... 1 4
Poly [ADP-ribose] polymerase 1 Inhibitor KU-0059436 Family 21 45
Pan-DAC Inhibitor AR-42 Family 21 153
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 9 5
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 3 1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 9 8
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 4 0
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 2 16
Adenosine receptor A3 ligand AGN-PC-09M0WF family 1 1
B1 bradykinin receptor ligand 4-(4-methyl-1-oxophthalazin-2-yl... 5 27
Melanin-concentrating hormone receptor 1 ligand N-[3-[1-[3-[4-... 4 13
Poly [ADP-ribose] polymerase 1 inhibitor 8-[[4-fluoro-3-(4-phe... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 19
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 5
Aldose reductase inhibitor 2-[3-[2-(3-fluoroanilino)-2-oxoethy... 3 4
Hepatocyte growth factor receptor ligand N'-(4,7-dichloro-2-ox... 3 3
Inosine-5'-monophosphate dehydrogenase inhibitor N-[4-bromo-3-... 1 0


External ID

Functional Category

Molecule Name

CFAMM00249641 CHEMBL370838 Bioactive SureCN3388659
CFAMM00249622 CHEMBL196450 Bioactive SureCN3385158
CFAMM00249609 CHEMBL514565 Bioactive N-[(Z)-[1-(cyclohexylmethyl)-2-oxoindol-3-ylidene]amino]benzamide
CFAMM00249666 CHEMBL370217 Bioactive SureCN3388183
CFAMM00249650 CHEMBL128017 Bioactive dihydropyridazinone 6b
CFAMM00249655 DNC005677 Investigative Drug KU-58684

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



27516 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543