CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1768
Family Name Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 Inhibitor Prifelone Family
No. of Seeds 2 No. of Other Members 32
Family Centroid CFAMM00250003 Functional Category Investigative Drug with Natural Product
Superfamily Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 Inhibitor Prifelone Superfamily
Class Class 2244

Cousin Family NamesSeedsMembers
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3'-(1-benzothien-2... 3 33
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 I... 2 19
Estradiol 17-beta-dehydrogenase 1 Inhibitor 16-(thiophen-2-yl)... 2 0
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-[5-(4-hydroxyphe... 21 16
Carbonic anhydrase 2 inhibitor SureCN10368300 family 1 0
Estradiol 17-beta-dehydrogenase 1 and Estradiol 17-beta-dehydr... 1 0
Histone deacetylase 6 inhibitor SureCN3098138 family 1 1


External ID

Functional Category

Molecule Name

CFAMM00249997 CHEMBL1277708 Bioactive SureCN22898
CFAMM00250003 DNC005708 Investigative Drug Prifelone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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